Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
LS-F1769 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the detection of Human POU5F1 / OCT4 in samples of Adherent Cell Cultures. It is based upon a Cell-Based assay principle.
Adherent Cell Cultures
Colorimetric - 450nm (TMB)
Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.
POU5F1 ElisaKit, Oct-4 ElisaKit, OCT3 ElisaKit, OCT4 ElisaKit, OTF4 ElisaKit, POU class 5 homeobox 1 ElisaKit, Octamer-binding protein 3 ElisaKit, Octamer-binding protein 4 ElisaKit, OTF-3 ElisaKit, Oct-3 ElisaKit, OTF3 ElisaKit
POU5F1 / OCT4 is a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms.