Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
LS-F2127 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the detection of Human MAP3K8 / TPL2 in samples of Adherent Cell Cultures. It is based upon a Cell-Based assay principle.
Adherent Cell Cultures
Colorimetric - 450nm (TMB)
Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.
MAP3K8 ElisaKit, C-COT ElisaKit, Cancer Osaka thyroid oncogene ElisaKit, COT ElisaKit, Ewing sarcoma transformant ElisaKit, EST ElisaKit, MEKK8 ElisaKit, Proto-oncogene c-Cot ElisaKit, TPL2 ElisaKit, Tumor progression locus 2 ElisaKit, Protein kinase cot ElisaKit, Tpl-2 ElisaKit, ESTF ElisaKit
Required for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF-alpha (TNF) during immune responses. Involved in the regulation of T-helper cell differentiation and IFNG expression in T-cells. Involved in mediating host resistance to bacterial infection through negative regulation of type I interferon (IFN) production.