Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Promyelocytic Leukemia Protein (PML)
No significant cross-reactivity or interference between Promyelocytic Leukemia Protein (PML) and analogs was observed.
LS-F7694 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the detection of Human PML in samples of Tissue Homogenates. It is based upon a Sandwich assay principle and can be used to detect levels of PML as low as 0.066 nanograms per millilter.
96-Well Strip Plate
Colorimetric - 450nm (TMB)
0.156 - 10 ng/ml
Intra-Assay: CV<10% Inter-Assay: CV<12%
Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.
PML ElisaKit, PP8675 ElisaKit, Promyelocytic leukemia ElisaKit, Protein PML ElisaKit, TRIM19 ElisaKit, Promyelocytic leukemia protein ElisaKit, RING finger protein 71 ElisaKit, MYL ElisaKit, RNF71 ElisaKit
Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. Acts as the scaffold of PML-NBs allowing other proteins to shuttle in and out, a process which is regulated by SUMO-mediated modifications and interactions.