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Catalog Number Size Price
LS-H4585-5 5 mg $60 
Biochemical

[Sar1, Ile8]-Angiotensin II - LS-H4585

[Sar1, Ile8]-Angiotensin II - LS-H4585

Description:
The biological activities of angiotensin II antagonists upon basal and angiotensin II-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation. Our investigations found that the most potent competitive antagonist of angiotensin II-stimulated aldosterone production was the [Sar1;Ile8] derivative of angiotensin II. However;this peptide was also a partial agonist at concentrations required to inhibit the steroidogenic effect of angiotensin II on dog adrenal cells;and never reduced aldosterone production to basal levels.
Price
Catalog Number
$60 
LS-H4585-5
5 mg
Toll Free North America
866-819-4732

Overview

Description:
The biological activities of angiotensin II antagonists upon basal and angiotensin II-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation. Our investigations found that the most potent competitive antagonist of angiotensin II-stimulated aldosterone production was the [Sar1;Ile8] derivative of angiotensin II. However;this peptide was also a partial agonist at concentrations required to inhibit the steroidogenic effect of angiotensin II on dog adrenal cells;and never reduced aldosterone production to basal levels.

Specifications

Biological Function
[Sar1, Ile8]-Angiotensin II was also a partial agonist at concentrations required to inhibit the steroidogenic effect of angiotensin ii on dog adrenal cells, and never reduced aldosterone production to basal levels. the biological activities of angiotensin ii antagonists upon basal and angiotensin ii-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation, our investigations found that the most potent competitive antagonist of angiotensin ii-stimulated aldosterone production was the [sar1, ile8] derivative of angiotensin ii.
Purity
Greater than 95%
Type
[Sar1, Ile8]-Angiotensin II, Angiotensin 2, Angiotensin2, AngiotensinII
Classification
Biochemical, Synthetic Peptide
Molecular Weight
968.15 kDa
Formulation
White powder
Solubility
GenScript angiotensin II is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
Sequence
{SAR}{ARG}{VAL}{TYR}{ILE}{HIS}{PRO}{ILE}
Storage
Store at -20°C.
Documents
Restrictions
For research use only.
Guarantee
This Biochemical carries the LSBio 100% Guarantee

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Requested From: United States
Date Requested: 12/7/2019