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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-H14606-5 5 mg $85 
LS-H14606-25 25 mg $285 
AR-A 014418 Biochemical - AR-A 014418 Structure

AR-A 014418 (CAS 487021-52-3) - LS-H14606

AR-A 014418 (CAS 487021-52-3) - LS-H14606

Available for shipment within the USA only
Description:
AR-A 014418 is a selective glycogen synthase kinase 3 (GSK-3) inhibitor, IC50 = 104 nM. Inhibits b-amyloid-mediated neurodegeneration in hippocampal slices. Anti-inflammatory activity. Cell permeable. Active in rodent models.
Price
Catalog Number
$85 
LS-H14606-5

Available for shipment within the USA only
Toll Free North America
866-819-4732

Overview

Description:
AR-A 014418 is a selective glycogen synthase kinase 3 (GSK-3) inhibitor, IC50 = 104 nM. Inhibits b-amyloid-mediated neurodegeneration in hippocampal slices. Anti-inflammatory activity. Cell permeable. Active in rodent models.

Specifications

CAS Number
487021-52-3
Biological Function
GSK-3 inhibitor
Purity
Greater than 98% by NMR, TLC
Formal Name
N-[(4-Methoxyphenyl)methyl]-N'-(5-nitro-2-thiazolyl)urea
Classification
Biochemical, Chemical, Inhibitor
Molecular Formula
C12H12N4O4S
Molecular Weight
308.32
Formulation
Off-white solid
Solubility
Soluble in DMSO (up to 30 mg/ml).
Storage
Store at -20°C. After dissolving store at -20°C for up to 2 months.
Stability
24 months
Documents
Restrictions
For research use only. Available for shipment within the USA only
Guarantee
This Biochemical carries the LSBio 100% Guarantee

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Images

AR-A 014418 Biochemical - AR-A 014418 Structure
AR-A 014418 Structure

AR-A 014418 Biochemical - AR-A 014418 Structure
AR-A 014418 Structure

AR-A 014418 Biochemical - AR-A 014418 Structure
AR-A 014418 Structure

AR-A 014418 Biochemical - AR-A 014418 Structure
AR-A 014418 Structure

Requested From: United States
Date Requested: 12/13/2019