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Catalog Number Size Price
LS-H14596-10 10 mg $60 
LS-H14596-50 50 mg $230 
Anagrelide HCl Biochemical - Anagrelide HCl Structure

Anagrelide HCl (CAS 58579-51-4) - LS-H14596

Anagrelide HCl (CAS 58579-51-4) - LS-H14596

Available for shipment within the USA only
Description:
Anagrelide HCl is a potent and selective phosphodiesterase (PDE3) inhibitor, IC50=36 nM). Inhibits platelet production by disrupting megakaryocyte maturation via a mechanism which is independent of PDE3 inhibition. Clinically useful agent for conditions requiring platelet lowering therapy.
Price
Catalog Number
$60 
LS-H14596-10

Available for shipment within the USA only
Toll Free North America
866-819-4732

Overview

Description:
Anagrelide HCl is a potent and selective phosphodiesterase (PDE3) inhibitor, IC50=36 nM). Inhibits platelet production by disrupting megakaryocyte maturation via a mechanism which is independent of PDE3 inhibition. Clinically useful agent for conditions requiring platelet lowering therapy.

Specifications

CAS Number
58579-51-4
Biological Function
PDE2 inhibitor
Purity
Greater than 98% (NMR, HPLC)
Formal Name
6,7-dichloro-1,5-dihydroimidazo[2,1 –b]quinazolin-2(3H)-one hydrochloride
Classification
Biochemical, Chemical, Inhibitor
Molecular Formula
C10H7Cl2N3O HCl
Molecular Weight
292.55
Formulation
White solid
Solubility
Soluble in DMSO (up to 2.5 mg/ml)
Storage
Store desiccated at -20°C. After dissolving store at -20°C for up to 3 months.
Stability
12 months
Documents
Restrictions
For research use only. Available for shipment within the USA only
Guarantee
This Biochemical carries the LSBio 100% Guarantee

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Images

Anagrelide HCl Biochemical - Anagrelide HCl Structure
Anagrelide HCl Structure

Anagrelide HCl Biochemical - Anagrelide HCl Structure
Anagrelide HCl Structure

Anagrelide HCl Biochemical - Anagrelide HCl Structure
Anagrelide HCl Structure

Anagrelide HCl Biochemical - Anagrelide HCl Structure
Anagrelide HCl Structure

Requested From: United States
Date Requested: 12/6/2019