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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-H14592-1 1 mg $70 
LS-H14592-5 5 mg $250 
Alsterpaullone Biochemical - Alsterpaullone Structure

Alsterpaullone (CAS 237430-03-4) - LS-H14592

Alsterpaullone (CAS 237430-03-4) - LS-H14592

Available for shipment within the USA only
Description:
Alsterpaullone is a potent and selective inhibitor of GSK-3b and CDK5/p25. Potent inhibitor of CDK1/cyclin B (IC50 = 35 nM). Alsterpaullone induces apoptosis and inhibits angiogenesis.
Price
Catalog Number
$70 
LS-H14592-1

Available for shipment within the USA only
Toll Free North America
866-819-4732

Overview

Description:
Alsterpaullone is a potent and selective inhibitor of GSK-3b and CDK5/p25. Potent inhibitor of CDK1/cyclin B (IC50 = 35 nM). Alsterpaullone induces apoptosis and inhibits angiogenesis.

Specifications

CAS Number
237430-03-4
Biological Function
GSK3ß inhibitor, CDK5/p25 inhibitor
Purity
Greater than 96% by TLC, NMR
Formal Name
9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5)-one
Classification
Biochemical, Chemical, Inhibitor
Molecular Formula
C16H11N3O3
Molecular Weight
293.28
Formulation
Brown solid
Solubility
Soluble in DMSO (up to 10 mg/ml).
Storage
Store desiccated at room temperature. After dissolving store at -20°C for up to 3 months.
Stability
24 months
Documents
Restrictions
For research use only. Available for shipment within the USA only
Guarantee
This Biochemical carries the LSBio 100% Guarantee

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Images

Alsterpaullone Biochemical - Alsterpaullone Structure
Alsterpaullone Structure

Alsterpaullone Biochemical - Alsterpaullone Structure
Alsterpaullone Structure

Alsterpaullone Biochemical - Alsterpaullone Structure
Alsterpaullone Structure

Alsterpaullone Biochemical - Alsterpaullone Structure
Alsterpaullone Structure

Requested From: United States
Date Requested: 12/11/2019