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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-H14588-5 5 mg $75 
LS-H14588-25 25 mg $200 
ALLM Biochemical - ALLM Structure

ALLM (CAS 136632-32-1) - LS-H14588

ALLM (CAS 136632-32-1) - LS-H14588

Available for shipment within the USA only
Description:
ALLM is a cell-permeable, peptide aldehyde inhibitor of calpain (calpain I, Ki = 120 nM, calpain II, Ki = 230 nM) and other neutral cysteine proteases. Potent inhibitor of cathepsin L (Ki=0.6 nM) and cathepsin B (Ki=100 nM). Weak inhibitor of the chymotrypsin-like activity of the proteasome. Cell permeable.
Price
Catalog Number
$75 
LS-H14588-5

Available for shipment within the USA only
Toll Free North America
866-819-4732

Overview

Description:
ALLM is a cell-permeable, peptide aldehyde inhibitor of calpain (calpain I, Ki = 120 nM, calpain II, Ki = 230 nM) and other neutral cysteine proteases. Potent inhibitor of cathepsin L (Ki=0.6 nM) and cathepsin B (Ki=100 nM). Weak inhibitor of the chymotrypsin-like activity of the proteasome. Cell permeable.

Specifications

CAS Number
136632-32-1
Biological Function
Calpain inhibitor
Purity
Greater than 98% (NMR, HPLC)
Formal Name
N-Acetyl-Leu-Leu-Methional
Classification
Biochemical, Chemical, Inhibitor
Molecular Formula
C19H35N3O4S
Molecular Weight
401.56
Formulation
White solid
Solubility
Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml).
Storage
Store at -20°C. After dissolving store at -20°C for up to 1 month.
Stability
12 months
Documents
Restrictions
For research use only. Available for shipment within the USA only
Guarantee
This Biochemical carries the LSBio 100% Guarantee

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Images

ALLM Biochemical - ALLM Structure
ALLM Structure

ALLM Biochemical - ALLM Structure
ALLM Structure

ALLM Biochemical - ALLM Structure
ALLM Structure

ALLM Biochemical - ALLM Structure
ALLM Structure

Requested From: United States
Date Requested: 12/13/2019