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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-H14492-50 50 mg $55 
LS-H14492-250 250 mg $195 
AICAR Biochemical - AICAR Structure

AICAR (CAS 2627-69-2) - LS-H14492

AICAR (CAS 2627-69-2) - LS-H14492

Available for shipment within the USA only
Description:
Activates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor. Promotes skeletal muscle autophagy via activation of FoxO3a. Controls smooth muscle cell hyperproliferation in vascular disease. Induces osteogenic differentiation in mesenchymal stem cells. Inhibits proinflammatory response in glial cells. Cell permeable. MP = 213-214°C
Price
Catalog Number
$55 
LS-H14492-50

Available for shipment within the USA only
Toll Free North America
866-819-4732

Overview

Description:
Activates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor. Promotes skeletal muscle autophagy via activation of FoxO3a. Controls smooth muscle cell hyperproliferation in vascular disease. Induces osteogenic differentiation in mesenchymal stem cells. Inhibits proinflammatory response in glial cells. Cell permeable. MP = 213-214°C

Specifications

CAS Number
2627-69-2
Biological Function
AMPK activator
Purity
Greater than 99% by TLC and NMR
Formal Name
5-Aminoimidazole-4-carboxamide 1-ß-D-ribofuranoside
Classification
Biochemical, Chemical, Ligand
Molecular Formula
C9H14N4O5
Molecular Weight
258.24
Formulation
Off-white solid
Solubility
Soluble in DMSO (up to 15 mg/ml) or in Water (up to 15 mg/ml).
Storage
Store at -20°C. After dissolving store at -20°C for up to 3 months.
Stability
24 months
Documents
Restrictions
For research use only. Available for shipment within the USA only
Guarantee
This Biochemical carries the LSBio 100% Guarantee

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Images

AICAR Biochemical - AICAR Structure
AICAR Structure

AICAR Biochemical - AICAR Structure
AICAR Structure

AICAR Biochemical - AICAR Structure
AICAR Structure

AICAR Biochemical - AICAR Structure
AICAR Structure

Requested From: United States
Date Requested: 12/8/2019