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Catalog Number Size Price
LS-H14584-10 10 mg $70 
LS-H14584-50 50 mg $230 
AdipoRon Biochemical - AdipoRon Structure

AdipoRon (CAS 924416-43-3) - LS-H14584

AdipoRon (CAS 924416-43-3) - LS-H14584

Available for shipment within the USA only
Description:
AdipoRon is a novel potent and selective adiponectin (AdipoR1 and AdipoR2) receptor agonist, Kd=1.8 and 3.1 uM respectively. Displayed similar effects to adiponectin in muscle and liver such as activation of PPARa and AMPK signaling pathways. It also reversed insulin resistance and glucose intolerance in mice on a high-fat diet. AdipoRon ameliorated diabetes in a genetically obese mouse model and prolonged the shortened lifespan of db/db mice on a high-fat diet. Attenuates PDGF-induced VSMC proliferation via inhibition of mTPR signaling in an AMPK independent manner. Active in vivo.
Price
Catalog Number
$70 
LS-H14584-10

Available for shipment within the USA only
Toll Free North America
866-819-4732

Overview

Description:
AdipoRon is a novel potent and selective adiponectin (AdipoR1 and AdipoR2) receptor agonist, Kd=1.8 and 3.1 uM respectively. Displayed similar effects to adiponectin in muscle and liver such as activation of PPARa and AMPK signaling pathways. It also reversed insulin resistance and glucose intolerance in mice on a high-fat diet. AdipoRon ameliorated diabetes in a genetically obese mouse model and prolonged the shortened lifespan of db/db mice on a high-fat diet. Attenuates PDGF-induced VSMC proliferation via inhibition of mTPR signaling in an AMPK independent manner. Active in vivo.

Specifications

CAS Number
924416-43-3
Biological Function
Adiponection agonist
Purity
Greater than 98% by NMR, TLC
Formal Name
2-(4-Benzylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide
Classification
Biochemical, Chemical, Agonist
Molecular Formula
C27H28N2O3
Molecular Weight
428.54
Formulation
White solid
Solubility
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 20 mg/ml).
Storage
Store at room temperature. After dissolving store at -20°C for up to 2 months.
Stability
12 months
Documents
Restrictions
For research use only. Available for shipment within the USA only
Guarantee
This Biochemical carries the LSBio 100% Guarantee

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AdipoRon Biochemical - AdipoRon Structure
AdipoRon Structure

AdipoRon Biochemical - AdipoRon Structure
AdipoRon Structure

AdipoRon Biochemical - AdipoRon Structure
AdipoRon Structure

AdipoRon Biochemical - AdipoRon Structure
AdipoRon Structure

Requested From: United States
Date Requested: 12/11/2019