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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cathepsin S Inhibitor Screening Kit (Fluorometric) - LS-K357

Available for shipment within the USA only
Assay Kit
100 asy

Available for shipment within the USA only

Product Description

Cathepsin S (CTSS, EC is a lysosomal cysteine proteinase that is suggested to participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The Cathepsin S Inhibitor Screening Kit utilizes the ability of Cathepsin S to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin S inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This high-throughput adaptable assay kit is simple, sensitive, and rapid tool to screen the potential inhibitors of Cathepsin S.


Cathepsin S Inhibitor Screening Kit (Fluorometric)
Product Type
Inhibitor Screening
Usage Summary
Screen/study/characterize potential inhibitors of Cathepsin S.
CTSS / Cathepsin S
Fluorometric (Ex/Em 400/505 nm)
Kit Components
  • CTSS Reaction Buffer
  • Cathepsin S (human)
  • CTSS Substrate
  • Z-VVR-AFC (10 mM)
  • CTSS Inhibitor (Z-FF-FMK
  • 1 mM)
  • (See Datasheet for specific volumes supplied)
  • Applications
    Spectrophotometry (fluorometric)
    Microplate fluorometer
    Shipped -20°C Dry Ice, Store at Store at -20°C for up to 1 year., 12 months shelf life.
    Data Sheet Data Sheet    SDS SDS
    For research use only. Available for shipment within the USA only.
    About CTSS / Cathepsin S
    P25774 NM_004079 NP_004070.3

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    Requested From: United States
    Date Requested: 5/20/2019
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