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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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XPO1 / CRM1 Antibody (aa809‑858, Biotin) LS‑C440428
CRM1 antibody LS-C440428 is a biotin-conjugated rabbit polyclonal antibody to CRM1 (XPO1) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C440428-100
100 µl (1 mg/ml)
$385

Popular XPO1 / CRM1 Products

Anti-CRM1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Species: Human, Monkey, Bat, Bovine, Dog, Horse, Chicken, Xenopus
Applications: IHC, IHC - Paraffin, Western blot
Fetal heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 6%-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit, Chicken, Xenopus
Applications: Western blot
Anti-XPO1 / CRM1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence
Anti-XPO1 / CRM1 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Proximity Ligation Assay
Immunohistochemistry of paraffin-embedded human pancreatic tissue using XPO1 Antibody at dilution of 1:100
Species: Human, Mouse
Applications: IHC, Immunofluorescence, Western blot, ELISA

Product Description

CRM1 antibody LS-C440428 is a biotin-conjugated rabbit polyclonal antibody to CRM1 (XPO1) from human, mouse, rat and other species. Validated for WB.

Specifications

Target
Human XPO1 / CRM1
Synonyms
XPO1, CRM1, yeast, homolog, Exp1, Exportin-1, CRM1
Host
Rabbit
Reactivity
Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit, Chicken, Xenopus (tested or 100% immunogen sequence identity)
Predicted
Zebrafish (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
XPO1 / CRM1 antibody was raised against synthetic peptide located between aa809-858 of human XPO1 (O14980, NP_003391). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Zebra finch, Chicken, Platypus, Xenopus (100%); Salmon, Zebrafish, Beetle (92%).
Epitope
aa809-858
Specificity
Human XPO1 / CRM1
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
About XPO1 / CRM1
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. O14980 NM_003400 NP_003391.1


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Images

Western blot

Fetal heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 6%-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 6%-18%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Fetal heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 6%-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 6%-18%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Fetal heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 6%-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 6%-18%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Fetal heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 6%-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 6%-18%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 11/16/2018

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