VIPERIN / RSAD2

radical S-adenosyl methionine domain containing 2

Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.

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Products

Antibodies (21)

ELISA Kits (7)

Proteins (5)

Type

Competitive EIA (1)

Custom (4)

Over-Expression Lysate (2)

Primary (21)

Recombinant (3)

Sandwich (2)

Target

VIPERIN / RSAD2 (33)

Reactivity

Human (24)

Mouse (14)

Rat (8)

Bovine (7)

Chicken (4)

Chimpanzee (3)

Dog (8)

Gibbon (3)

Guinea pig (3)

Hamster (4)

Horse (4)

Monkey (3)

Orangutan (3)

Pig (8)

Rabbit (4)

Zebrafish (3)

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Application

IHC (9)

IHC-P (7)

WB (20)

Flo (1)

ELISA (4)

IF (5)

IP (2)

Peptide-ELISA (1)

Host

rabbit (18)

mouse (3)

Product Group

IHCPlus (2)

Isotype

IgG (16)

IgG2a (1)

IgG2b (2)

Clonality

monoclonal mc (3)

polyclonal pc (18)

Clone

MaP.VIP (1)

OTI4D12 (2)

Format

96-Well Strip Plate (7)

Biotin Conjugated (2)

Carrier-free (1)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (15)

Epitope

C-Terminus (4)

aa101-150 (4)

aa42-361 (2)

N-Terminus (1)

aa165-215 (1)

aa92-362 (1)

Publications

No (33)

Sample Type

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

VIPERIN / RSAD2 Antibody (aa92-362, clone MaP.VIP) LS-C139851

Antibody:

VIPERIN / RSAD2 Mouse anti-Mouse Monoclonal (aa92-362) (MaP.VIP) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$589

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VIPERIN / RSAD2 Antibody (C-Terminus) LS-C31916

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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VIPERIN / RSAD2 Antibody (C-Terminus, HRP) LS-C444123

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Zebrafish, Pig, Rabbit, Mouse, Dog, Bovine, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

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VIPERIN / RSAD2 Antibody (C-Terminus, Biotin) LS-C444121

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Zebrafish, Pig, Rabbit, Mouse, Dog, Bovine, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

VIPERIN / RSAD2 Antibody (C-Terminus, FITC) LS-C444122

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Zebrafish, Pig, Rabbit, Mouse, Dog, Bovine, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

IHC-plus™ VIPERIN / RSAD2 Antibody LS-B15483

(4.0) Rating

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

VIPERIN / RSAD2 Antibody (aa42-361) LS-C378833

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (aa42-361) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

VIPERIN / RSAD2 Antibody LS-C802732

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

VIPERIN / RSAD2 Antibody (aa165-215) LS-C148858

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (aa165-215) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Pig, Horse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$386

Select

VIPERIN / RSAD2 Antibody (aa101-150) LS-C31915

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (aa101-150) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

VIPERIN / RSAD2 Antibody (aa101-150, HRP) LS-C444120

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (aa101-150) (HRP) Antibody

Reactivity:

Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Orangutan, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

VIPERIN / RSAD2 Antibody (aa101-150, Biotin) LS-C444118

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (aa101-150) (Biotin) Antibody

Reactivity:

Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Orangutan, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

VIPERIN / RSAD2 Antibody (aa101-150, FITC) LS-C444119

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (aa101-150) (FITC) Antibody

Reactivity:

Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Orangutan, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

VIPERIN / RSAD2 Antibody (clone OTI4D12) LS-C174525

Antibody:

VIPERIN / RSAD2 Mouse anti-Human Monoclonal (OTI4D12) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

VIPERIN / RSAD2 Antibody (clone OTI4D12, Carrier-free) LS-C797657

Antibody:

VIPERIN / RSAD2 Mouse anti-Human Monoclonal (Carrier-free) (OTI4D12) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

VIPERIN / RSAD2 Antibody LS-C343717

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µg/$571

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VIPERIN / RSAD2 Antibody LS-C755108

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

Human VIPERIN / RSAD2 (Sandwich ELISA) ELISA Kit - LS-F13431

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

IHC-plus™ VIPERIN / RSAD2 Antibody (aa42-361) LS-B15163

(4.0) Rating

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (aa42-361) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$460

Select

VIPERIN / RSAD2 Antibody LS-C743330

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

VIPERIN / RSAD2 Antibody LS-C770391

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

VIPERIN / RSAD2 Antibody (N-Terminus) LS-C358085

Antibody:

VIPERIN / RSAD2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Dog, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

25 µg/$364; 100 µg/$511

Select

Human VIPERIN / RSAD2 (Competitive EIA) ELISA Kit - LS-F39378

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human VIPERIN / RSAD2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67646

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42 kDa

Price:

20 µg/$1,107

Select

Human VIPERIN / RSAD2 Protein (Recombinant GST, N-terminus) (aa262-361) - LS-G63474

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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