VIL1 / Villin

villin 1

Epithelial cell-specific Ca2+-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity. Regulates the intestinal epithelial cell morphology, cell invasion, cell migration and apoptosis. Protects against apoptosis induced by dextran sodium sulfate (DSS) in the gastrointestinal epithelium. Appears to regulate cell death by maintaining mitochondrial integrity. Enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, chemotaxis and wound repair. Upon S.flexneri cell infection, its actin-severing activity enhances actin-based motility of the bacteria and plays a role during the dissemination.

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Products

Antibodies (46)

ELISA Kits (10)

Proteins (8)

Type

Custom (3)

Development Kit (1)

Over-Expression Lysate (2)

Primary (46)

Recombinant (6)

Sandwich (5)

Sandwich CLIA (1)

Target

VIL1 / Villin (64)

Reactivity

Human (52)

Mouse (23)

Rat (6)

Chicken (1)

Chimpanzee (3)

Horse (3)

Monkey (3)

Orangutan (3)

Pig (9)

Application

IHC (15)

IHC-Fr (4)

IHC-P (20)

WB (32)

Flo (6)

ELISA (6)

ICC (2)

IF (7)

Peptide-ELISA (1)

PMA (2)

Host

rabbit (26)

mouse (20)

Product Group

DevKit DuoPlus (1)

IHCPlus (5)

PathPlus Cancer (3)

PathPlus Cancer Pathology (3)

Isotype

IgG (11)

IgG1 (10)

IgG1,k (6)

IgG2b (1)

IgG2b,k (2)

Clonality

monoclonal mc (18)

polyclonal pc (24)

recombinant monoclonal rmc (4)

Clone

3E5G11 (1)

3G6 (1)

5E3B2 (1)

CWWB1 (4)

OTI3B3 (2)

rVIL1/1325 (2)

UMAB230 (2)

VIL1/1314 (2)

VIL1/1325 (2)

VIL1/2310R (2)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (7)

Antibody Pair and Standard (1)

APC (1)

APC Conjugated (1)

Azide-free (4)

Biotin Conjugated (2)

BSA-free (2)

Carrier-free (4)

Concentrated (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Ready-to-Use (1)

Unconjugated (36)

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Epitope

aa1-320 (8)

C-Terminus (5)

aa1-188 (4)

aa179-311 (4)

aa1-350 (1)

aa180-207 (1)

aa7-246 (1)

aa770-799 (1)

Publications

No (63)

Yes (1)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (2)

Plasma (5)

Serum (5)

Tissue Homogenates (4)

Tag

GST (2)

GST, N-terminus (1)

His, N-Terminal (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (3)

Purification

Purified (3)

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VIL1 / Villin Antibody (aa770-799) LS-C407669

(4.1) Rating

(2) Publication(s)

Antibody:

VIL1 / Villin Rabbit anti-Human Polyclonal (aa770-799) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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IHC-plus™ VIL1 / Villin Antibody LS-B2581

(4.0) Rating

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$605

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IHC-plus™ VIL1 / Villin Antibody LS-B13880

(4.0) Rating

Antibody:

VIL1 / Villin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ VIL1 / Villin Antibody (aa7-246) LS-B16397

(4.0) Rating

Antibody:

VIL1 / Villin Rabbit anti-Human Polyclonal (aa7-246) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Human VIL1 / Villin (Sandwich ELISA) ELISA Kit - LS-F13957

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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VIL1 / Villin Antibody (clone CWWB1) LS-C312202

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal (CWWB1) Antibody

Reactivity:

Human

Applications:

IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.1 ml/$327

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IHC-plus™ VIL1 / Villin Antibody (clone CWWB1) LS-B16185

(4.0) Rating

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal (CWWB1) Antibody

Reactivity:

Human

Applications:

IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.05 ml/$460

• Unconjugated
• Unconjugated

• Unconjugated
• Unconjugated

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VIL1 / Villin Antibody (aa1-320, APC) LS-C717915

Antibody:

VIL1 / Villin Rabbit anti-Human Polyclonal (aa1-320) (APC) Antibody

Reactivity:

Mouse, Pig, Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

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VIL1 / Villin Antibody (aa180-207) LS-C160527

Antibody:

VIL1 / Villin Rabbit anti-Human Polyclonal (aa180-207) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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VIL1 / Villin Antibody (C-Terminus) LS-C76819

Antibody:

VIL1 / Villin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$688

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PathPlus™ VIL1 / Villin Antibody LS-B16167

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$460

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VIL1 / Villin Antibody (clone 3E5G11) LS-C669195

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal (3E5G11) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

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VIL1 / Villin Antibody (clone VIL1/1325) LS-C761950

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal (VIL1/1325) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC-P, WB

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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VIL1 / Villin Antibody (clone VIL1/1325, Azide-free, BSA-free) LS-C761952

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (VIL1/1325) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC-P, WB

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

• Unconjugated
• Unconjugated, Azide-free, BSA-free

• Unconjugated
• Unconjugated, Azide-free, BSA-free

Select

VIL1 / Villin Antibody (clone VIL1/1314) LS-C761949

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal (VIL1/1314) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC-P, WB

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

Select

VIL1 / Villin Antibody (clone VIL1/1314, Azide-free, BSA-free) LS-C761948

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (VIL1/1314) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC-P, WB

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

• Unconjugated
• Unconjugated, Azide-free, BSA-free

• Unconjugated
• Unconjugated, Azide-free, BSA-free

Select

VIL1 / Villin Antibody (C-Terminus, FITC) LS-C472678

Antibody:

VIL1 / Villin Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Mouse, Horse, Orangutan, Human, Monkey, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

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Mouse VIL1 / Villin (Sandwich ELISA) ELISA Kit - LS-F13960

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Human VIL1 / Villin (Sandwich ELISA) ELISA Kit - LS-F7927

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

Select

PathPlus™ VIL1 / Villin Antibody (aa179-311, clone rVIL1/1325) LS-B16262

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

VIL1 / Villin Mouse anti-Human Recombinant Monoclonal (aa179-311) (rVIL1/1325) Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µg/$485

Select

PathPlus™ VIL1 / Villin Antibody (aa179-311, clone VIL1/2310R) LS-B16304

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

VIL1 / Villin Rabbit anti-Human Recombinant Monoclonal (aa179-311) (VIL1/2310R) Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µg/$525

Select

VIL1 / Villin Antibody (clone 5E3B2) LS-C669186

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal (5E3B2) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

VIL1 / Villin Antibody LS-C490133

Antibody:

VIL1 / Villin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

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VIL1 / Villin Antibody (aa1-188, clone UMAB230) LS-C797008

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal (aa1-188) (UMAB230) Antibody

Reactivity:

Human

Applications:

IHC, PMA

Format:

Unconjugated

Price:

100 µl/$493

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VIL1 / Villin Antibody (aa1-188, clone UMAB230, Carrier-free) LS-C797009

Antibody:

VIL1 / Villin Mouse anti-Human Monoclonal (aa1-188) (Carrier-free) (UMAB230) Antibody

Reactivity:

Human

Applications:

IHC, PMA

Format:

Unconjugated, Carrier-free

Price:

100 µg/$539

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Viewing 1-25 of 64 product results

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