order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
USP9X / FAM
ubiquitin specific peptidase 9, X-linked
Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.
| Gene Name: | ubiquitin specific peptidase 9, X-linked |
| Family/Subfamily: | Protease , Cysteine C19 |
| Synonyms: | USP9X, DFFRX, FAM, Fat facets in mammals, HFAM, Ubiquitin thioesterase FAF-X, USP9, Deubiquitinating enzyme FAF-X, FAF, Ubiquitin thiolesterase FAF-X |
| Target Sequences: | NM_001039590 NP_001034679.2 Q93008 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
