ULK1

unc-51 like autophagy activating kinase 1

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.

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Products

Antibodies (90)

Proteins (5)

ELISA Kits (1)

Type

Over-Expression Lysate (2)

Primary (90)

Recombinant (3)

Sandwich (1)

Target

ULK1 (96)

Reactivity

Human (91)

Mouse (24)

Rat (21)

Bovine (3)

Chicken (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Hamster (3)

Horse (3)

Insect (3)

Monkey (4)

Orangutan (3)

Pig (3)

Rabbit (3)

Xenopus (3)

Zebrafish (3)

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Application

IHC (10)

IHC-P (3)

WB (56)

Flo (1)

DB (28)

ELISA (56)

IF (15)

IP (1)

Peptide-ELISA (2)

Host

rabbit (88)

mouse (1)

sheep (1)

Product Group

IHCPlus (2)

Isotype

IgG (67)

IgG1,k (1)

Clonality

monoclonal mc (2)

polyclonal pc (88)

Clone

2H8 (1)

D1H4 (1)

Format

96-Well Strip Plate (1)

AP Conjugated (1)

APC Conjugated (9)

Atto 390 Conjugated (1)

Atto 488 Conjugated (1)

Atto 594 Conjugated (1)

Azide-free (8)

Biotin Conjugated (11)

FITC Conjugated (11)

HRP Conjugated (10)

PE Conjugated (8)

PerCP Conjugated (1)

RPE Conjugated (1)

Unconjugated (35)

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Epitope

pSer556 (15)

aa296-322 (7)

aa538-564 (7)

pSer317 (7)

pSer467 (7)

aa642-672 (6)

Internal (5)

aa190-239 (4)

aa350-410 (2)

pSer555 (2)

C-terminal (1)

Ser638 (1)

Ser757 (1)

aa400-499 (1)

aa542-565 (1)

aa670-700 (1)

pSer757 (1)

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Publications

No (96)

Sample Type

Plasma (1)

Serum (1)

Tissue Homogenates (1)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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IHC-plus™ ULK1 Antibody LS-B10104

(4.0) Rating

Antibody:

ULK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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IHC-plus™ ULK1 Antibody LS-B1811

(4.0) Rating

Antibody:

ULK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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ULK1 Antibody (clone 2H8) LS-C198556

Antibody:

ULK1 Mouse anti-Human Monoclonal (2H8) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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ULK1 Antibody LS-C167359

Antibody:

ULK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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ULK1 Antibody (aa190-239) LS-C186697

Antibody:

ULK1 Rabbit anti-Human Polyclonal (aa190-239) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ULK1 Antibody (aa350-410) LS-C95207

Antibody:

ULK1 Sheep anti-Human Polyclonal (aa350-410) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

500 µg/$393

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ULK1 Antibody (phospho-Ser555, clone D1H4) LS-C184156

Antibody:

ULK1 Rabbit anti-Human Monoclonal (pSer555) (D1H4) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$689

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Human ULK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88191

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

112.4 kDa

Price:

20 µg/$215

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Human ULK1 Protein (Recombinant GST) (Full Length) - LS-G31140

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

142.45 kDa

Price:

2 µg/$439

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ULK1 Antibody LS-C834551

Antibody:

ULK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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ULK1 Antibody LS-C661437

Antibody:

ULK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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ULK1 Antibody LS-C773174

Antibody:

ULK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µg/$442

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ULK1 Antibody (aa542-565) LS-C806751

Antibody:

ULK1 Rabbit anti-Human Polyclonal (aa542-565) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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ULK1 Antibody (phospho-Ser556) LS-C809699

Antibody:

ULK1 Rabbit anti-Human Polyclonal (pSer556) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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ULK1 Antibody LS-C682272

Antibody:

ULK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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ULK1 Antibody (C-terminal) LS-C386605

Antibody:

ULK1 Rabbit anti-Human Polyclonal (C-terminal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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ULK1 Antibody (aa350-410) LS-C95225

Antibody:

ULK1 Rabbit anti-Human Polyclonal (aa350-410) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

500 µg/$393

Select

ULK1 Antibody (Biotin) LS-C773178

Antibody:

ULK1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Biotin Conjugated

Price:

100 µg/$477

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ULK1 Antibody (FITC) LS-C773182

Antibody:

ULK1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

FITC Conjugated

Price:

100 µg/$473

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ULK1 Antibody (APC) LS-C773177

Antibody:

ULK1 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

APC Conjugated

Price:

100 µg/$479

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ULK1 Antibody (AP) LS-C773176

Antibody:

ULK1 Rabbit anti-Human Polyclonal (AP) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

AP Conjugated

Price:

100 µg/$474

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ULK1 Antibody (PerCP) LS-C775713

Antibody:

ULK1 Rabbit anti-Human Polyclonal (PerCP) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

PerCP Conjugated

Price:

100 µg/$479

Select

ULK1 Antibody (RPE) LS-C775714

Antibody:

ULK1 Rabbit anti-Human Polyclonal (RPE) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

RPE Conjugated

Price:

100 µg/$477

Select

ULK1 Antibody (Atto 390) LS-C775716

Antibody:

ULK1 Rabbit anti-Human Polyclonal (Atto 390) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Atto 390 Conjugated

Price:

100 µg/$480

Select

ULK1 Antibody (Atto 488) LS-C775717

Antibody:

ULK1 Rabbit anti-Human Polyclonal (Atto 488) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Atto 488 Conjugated

Price:

100 µg/$479

• Biotin
• FITC
• APC
• AP
• PerCP
• RPE
• Atto 390
• More...
  • Atto 488

• Biotin
• FITC
• APC
• More...
  • AP
  • PerCP
  • RPE
  • Atto 390
  • Atto 488

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