UFM1 | BM-002 | C13orf20 | BA131P10.1 | Ubiquitin-fold modifier 1
(tested or 100% immunogen sequence identity)
Also available Unconjugated
or conjugated with HRP
Protein G purified
- Applications tested for the base form of this product only
Recombinant Human Ubiquitin-fold modifier 1 protein (11-63AA)
Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes. TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (Probable).
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
For research use only. Intended for use by laboratory professionals.
This antibody carries the LSBio 100% Guarantee.