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UBA1 / UBE1

ubiquitin-like modifier activating enzyme 1

Ubiquitin Activating Enzyme (E1), also known as A1S9 and UBE1, is responsible for the first step in ubiquitin-protein isopeptide bond formation. E1 catalyzes the activation of the Cterminal carboxyl group of ubiquitin by forming a high-energy thioester bond in an ATP-dependent manner. UBE1 is monomeric and contains two active sites within the E1 molecule, allowing it to bind two ubiquitin moieties at a time, with a new ubiquitin forming an adenylate intermediate as the previous one is transferred to the thiol site. Alternative splicing results in 2 transcript variants encoding the same protein, but with different 5' UTR. Isoform 1 has a different 5' noncoding exon compared to isoform 2. Both variants encode the same protein.

Gene Name: ubiquitin-like modifier activating enzyme 1
Synonyms: UBA1, A1S9, A1ST, A1S9T, AMCX1, GXP1, Protein A1S9, SMAX2, Ubiquitin-activating enzyme E1, UBE1X, POC20, UBE1, UBA1A
Target Sequences: NM_003334 NP_003325.2 P22314

☰ Filters
Antibodies (40)
Proteins (8)
ELISA Kits (2)
Competitive EIA (1)
Over-Expression Lysate (4)
Primary (40)
Recombinant (4)
Sandwich (1)
UBA1 / UBE1 (50)
Human (41)
Mouse (19)
Rat (12)
Bat (3)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Horse (4)
Monkey (3)
Pig (4)
Rabbit (4)
Sheep (1)
IHC (22)
IHC-P (6)
WB (35)
Flo (1)
ELISA (21)
ICC (1)
IF (2)
IP (5)
Peptide-ELISA (1)
rabbit (38)
mouse (2)
Product Group
IHCPlus (3)
IgG (30)
IgG2a,k (1)
monoclonal mc (2)
polyclonal pc (38)
2B6 (1)
96-Well Strip Plate (2)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (24)
aa1-30 (7)
aa1026-1058 (6)
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aa800-850 (2)
aa1-50 (1)
aa1008-1058 (1)
aa102-139 (1)
aa850-900 (1)
No (50)
Plasma (2)
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UBA1 / UBE1 Antibody - Anti-Ubiquitin Activating Enzyme Antibody - Immunohistochemistry. Affinity Purified anti-Ubiquitin Activating Enzyme antibody was used at a 10 ug/ml to detect UBE1 in a variety of tissues including adrenal, breast, colon (epithelium), kidney, liver, lung (respiratory epithelium), ovary (oocyte and endothelium), pancreas (islet and exocrine), placenta, prostate (epithelium), skin (epithelium), spleen (lymphocytes), stomach (chief), testis, thymus, tonsil, and uterus (glandular, stroma). In many cells a punctate nuclear staining was observed. Other cells showed both cytoplasmic and nuclear staining. This image shows UBE1 staining of human lung tissue. Tissue was formalin-fixed and paraffin embedded. Personal Communi-cation, Tina Roush, LifeSpanBiosciences, Seattle, WA.
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UBA1 / UBE1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
500 µg/$606
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ELISA, Flo, ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$688
UBA1 / UBE1 Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa800-850) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
UBA1 / UBE1 Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1008-1058) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
UBA1 / UBE1 Antibody - UBA1 / UBE1 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
UBA1 / UBE1 Antibody - Anti-UBA1 / UBE1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa800-850) Antibody
Human
IHC, IHC-P
Unconjugated
50 µl/$460
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1026-1058) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1026-1058) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1026-1058) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1026-1058) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1026-1058) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1026-1058) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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UBA1 / UBE1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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UBA1 / UBE1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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UBA1 / UBE1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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UBA1 / UBE1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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UBA1 / UBE1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µl/$412
UBA1 / UBE1 Antibody - UBA1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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UBA1 / UBE1 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
UBA1 / UBE1 Antibody - UBA1 monoclonal antibody (M02), clone 2B6. Western Blot analysis of UBA1 expression in HeLa.
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UBA1 / UBE1 Mouse anti-Human Monoclonal (2B6) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Viewing 1-25 of 50 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).