TXNIP

thioredoxin interacting protein

May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).

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Antibodies (61)

ELISA Kits (10)

Proteins (10)

Type

Custom (2)

Over-Expression Lysate (2)

Primary (61)

Recombinant (8)

Sandwich (8)

Target

TXNIP (81)

Reactivity

Human (47)

Mouse (32)

Rat (13)

Bat (6)

Bovine (6)

Chimpanzee (9)

Dog (9)

Gibbon (6)

Guinea pig (3)

Monkey (7)

Orangutan (6)

Pig (4)

Rabbit (6)

Sheep (3)

Xenopus (3)

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Application

IHC (11)

IHC-P (6)

WB (50)

ELISA (20)

IF (4)

IP (4)

Peptide-ELISA (1)

Host

rabbit (59)

mouse (2)

Product Group

IHCPlus (3)

Isotype

IgG (32)

IgG1 (1)

IgG2b (1)

Clonality

monoclonal mc (2)

polyclonal pc (59)

Clone

JY1 (1)

JY2 (1)

Format

96-Well Microplate (3)

96-Well Strip Plate (7)

APC (2)

APC Conjugated (4)

Azide-free (2)

Biotin Conjugated (9)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (9)

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PE Conjugated (4)

Unconjugated (22)

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Epitope

aa30-381 (8)

aa32-367 (8)

aa1-30 (7)

aa116-145 (7)

C-Terminus (4)

aa121-170 (4)

aa65-114 (4)

N-Terminus (1)

aa100-150 (1)

aa300-350 (1)

Publications

No (80)

Yes (1)

Sample Type

Cell Lysates (1)

Plasma (7)

Serum (6)

Tissue Homogenates (3)

Tag

6His, N-terminus (1)

6His-B2M, N-terminus (2)

6His-SUMO, N-terminus (1)

GST, N-terminus (1)

His (1)

His-GST (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Mouse (3)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (5)

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TXNIP Antibody (C-Terminus) LS-B5829

(4.0) Rating

(1) Publication(s)

Antibody:

TXNIP Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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TXNIP Antibody (clone JY2) LS-C179729

Antibody:

TXNIP Mouse anti-Human Monoclonal (JY2) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µg/$477

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IHC-plus™ TXNIP Antibody LS-B12126

(4.0) Rating

Antibody:

TXNIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$440

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TXNIP Antibody (aa116-145) LS-C157966

Antibody:

TXNIP Rabbit anti-Mouse Polyclonal (aa116-145) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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Mouse TXNIP Protein (Recombinant 6His-B2M, N-terminus) (aa1-397) - LS-G56812

Source:

E. coli

Tag:

6His-B2M, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human TXNIP (Sandwich ELISA) ELISA Kit - LS-F12885

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$783

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TXNIP Antibody (aa116-145, PE) LS-C224553

Antibody:

TXNIP Rabbit anti-Mouse Polyclonal (aa116-145) (PE) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

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TXNIP Antibody (aa100-150) LS-C148750

Antibody:

TXNIP Rabbit anti-Human Polyclonal (aa100-150) Antibody

Reactivity:

Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$386

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TXNIP Antibody (aa121-170) LS-C117038

Antibody:

TXNIP Rabbit anti-Human Polyclonal (aa121-170) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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IHC-plus™ TXNIP Antibody (aa300-350) LS-B15082

(4.0) Rating

Antibody:

TXNIP Rabbit anti-Human Polyclonal (aa300-350) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP

Format:

Unconjugated

Price:

50 µl/$460

Select

TXNIP Antibody LS-C661350

Antibody:

TXNIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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TXNIP Antibody LS-C410876

Antibody:

TXNIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Mouse TXNIP Protein (Recombinant 6His, N-terminus) (aa1-397) - LS-G57326

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Rat TXNIP (Sandwich ELISA) ELISA Kit - LS-F56338

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat TXNIP (Sandwich ELISA) ELISA Kit - LS-F16254

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Human TXNIP Protein (Recombinant His) (aa32-367) - LS-G24224

Source:

E. coli

Tag:

His

Molecular Weight:

41.1 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Mouse TXNIP Protein (Recombinant His-GST) (aa30-381) - LS-G24225

Source:

E. coli

Tag:

His-GST

Molecular Weight:

69.4 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Human TXNIP (Sandwich ELISA) ELISA Kit - LS-F21162

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Human TXNIP Protein (Recombinant GST, N-terminus) (Full Length) - LS-G32267

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Molecular Weight:

70.1 kDa

Price:

2 µg/$439

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Human TXNIP (Sandwich ELISA) ELISA Kit - LS-F27265

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

TXNIP Antibody LS-C806718

Antibody:

TXNIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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TXNIP Antibody LS-C671905

Antibody:

TXNIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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TXNIP Antibody (FITC) LS-C671906

Antibody:

TXNIP Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• FITC

• Unconjugated
• FITC

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TXNIP Antibody LS-C771531

Antibody:

TXNIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

TXNIP Antibody LS-C771532

Antibody:

TXNIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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