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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-C152788-100 100 µg (1 mg/ml) $515 
TRXR1 / TXNRD1 Antibody - ICC: CMXRos (a mitochondrial marker; 1:8000 dilution; Molecular Probes; red staining) was added to U937 cells growing in suspension, which were then incubated at 37°C for 30 min. Cells were fixed in paraformaldehyde and permeabilized. Cells were then incubated in blocking buffer (5% normal goat serum in PBS plus 0.05% Tween 20), and then in anti-TrxR1 (TrxR1; 1:100 dilution; green staining). After washing, cells were incubated with an anti-rabbit-Alexa 488 secondary antibody conjugate (1:100 dilution; Molecular Probes), washed, mounted in DAPI (blue staining) containing medium, and visualized in an Olympus IX71 confocal fluorescent microscope. Data generously provided by Ismael Samudio, Dept. of Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center.
TRXR1 / TXNRD1 Antibody - WB: 40 micrograms of rat brain microsomal preparation was probed with anti-Thioredoxin Reductase 1 (1g/ml)
TRXR1 / TXNRD1 Antibody - ICC: CMXRos (a mitochondrial marker; 1:8000 dilution; Molecular Probes; red staining) was added to U937 cells growing in suspension, which were then incubated at 37°C for 30 min. Cells were fixed in paraformaldehyde and permeabilized. Cells were then incubated in blocking buffer (5% normal goat serum in PBS plus 0.05% Tween 20), and then in anti-TrxR1 (TrxR1; 1:100 dilution; green staining). After washing, cells were incubated with an anti-rabbit-Alexa 488 secondary antibody conjugate (1:100 dilution; Molecular Probes), washed, mounted in DAPI (blue staining) containing medium, and visualized in an Olympus IX71 confocal fluorescent microscope. Data generously provided by Ismael Samudio, Dept. of Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center.
TRXR1 / TXNRD1 Antibody - WB: 40 micrograms of rat brain microsomal preparation was probed with anti-Thioredoxin Reductase 1 (1g/ml)
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TRXR1 / TXNRD1 Antibody (aa137‑150) LS‑C152788

TRXR1 / TXNRD1 Antibody (aa137‑150) LS‑C152788

Note: This antibody replaces LS-C18077
Antibody:
Rabbit Polyclonal to Human TRXR1 / TXNRD1
Application:
ICC, WB
Reactivity:
Human, Monkey, Rat, Bovine, Dog, Guinea pig, Pig
Format:
Unconjugated, Unmodified
Price
Catalog Number
$515 
LS-C152788-100
100 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human TRXR1 / TXNRD1
Application:
ICC, WB
Reactivity:
Human, Monkey, Rat, Bovine, Dog, Guinea pig, Pig
Format:
Unconjugated, Unmodified

Specifications

Description
TXNRD1 antibody LS-C152788 is an unconjugated rabbit polyclonal antibody to TXNRD1 (TRXR1 ) from human, rat, bovine and other species. Validated for ICC and WB.
Target
Human TRXR1 / TXNRD1
Host
Rabbit
Reactivity
Human, Monkey, Rat, Bovine, Dog, Guinea pig, Pig (tested or 100% immunogen sequence identity)
Predicted
Mouse, Bat, Horse, Rabbit (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • ICC
  • Western blot
Immunogen
Peptide corresponding to amino acids 137-150 (C-PHRIKATNNKGKEK) of human thioredoxin reductase 1 Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Panda, Dog, Bovine, Pig, Guinea pig (100%); Mouse, Elephant, Bat, Rabbit, Horse, Opossum (93%); Rat (86%).
Epitope
aa137-150
Specificity
Thioredoxin reductase 1
Presentation
0.1 M Tris-Glycine, pH 7.4, 0.15 M NaCl, 0.05% Sodium Azide, 30% Glycerol
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TRXR1 / TXNRD1
Q16881 NM_003330 NP_003321.3

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Requested From: United States
Date Requested: 11/12/2019