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| Catalog Number | Size | Price |
|---|---|---|
| LS-C94498-100 | 100 µl | $393 |
Polyclonal Rabbit anti‑Mouse TRPV4 Antibody (aa100‑150, IHC, IF, WB) LS‑C94498
Polyclonal Rabbit anti‑Mouse TRPV4 Antibody (aa100‑150, IHC, IF, WB) LS‑C94498
Antibody:
TRPV4 Rabbit anti-Mouse Polyclonal (aa100-150) Antibody
Application:
IHC, IHC-P, IF, WB
Reactivity:
Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
TRPV4 Rabbit anti-Mouse Polyclonal (aa100-150) Antibody
Application:
IHC, IHC-P, IF, WB
Reactivity:
Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
TRPV4 antibody LS-C94498 is an unconjugated rabbit polyclonal antibody to TRPV4 (aa100-150) from mouse. It is reactive with mouse and rat. Validated for IF, IHC and WB. Cited in 11 publications.
Target
Mouse TRPV4
Synonyms
TRPV4 | CMT2C | HMSN2C | OTRPC4 | SSQTL1 | VR-OAC | VRL-2 | Osm-9-like TRP channel 4 | SPSMA | TRP12 | VRL2 | VROAC | SMAL
Host
Rabbit
Reactivity
Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Immunogen
Synthetic peptide from 1t cytoplasmic domain of mouse TRPV4 conjugated to an immunogenic carrier protein.
Epitope
aa100-150
Specificity
Specific for TRPV4.
Applications
- IHC
- IHC - Paraffin
- Immunofluorescence
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
IHC: Antigen retrieval is essential for use on paraffin sections.
Presentation
Lyophilized
Reconstitution
Reconstitute with 100 µl sterile water.
Storage
Maintain lyophilized and reconstituted antibodies at -20°C for long term storage and at 2°C to 8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TRPV4
LSBio Ratings
TRPV4 Antibody (aa100-150) for IHC, IF/Immunofluorescence, WB/Western LS-C94498 has an LSBio Rating of
Publications (5)
Learn more about The LSBio Ratings Algorithm
Publications (11)
The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells. Ryskamp DA, Witkovsky P, Barabas P, Huang W, Koehler C, Akimov NP, Lee SH, Chauhan S, Xing W, Rentera RC, Liedtke W, Krizaj D. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 31:7089-101. (WB, IHC-Fr; Mouse, Human)
Neurite outgrowth and synaptophysin expression of postnatal CNS neurons on GaP nanowire arrays in long-term retinal cell culture. Piret G, Perez MT, Prinz CN. Biomaterials. 2013 34:875-87. (ICC, IHC-Fr; Mouse)
Dual contribution of TRPV4 antagonism in the regulatory effect of vasoinhibins on blood-retinal barrier permeability: diabetic milieu makes a difference. Arredondo Zamarripa D, Noguez Imm R, Bautista Cortés AM, Vázquez Ruíz O, Bernardini M, Fiorio Pla A, Gkika D, Prevarskaya N, López-Casillas F, Liedtke W, Clapp C, Thébault S. Scientific reports. 2017 7:13094. (IHC; Rat)
Polarity of varicosity initiation in central neuron mechanosensation. Gu Y, Jukkola P, Wang Q, Esparza T, Zhao Y, Brody D, Gu C,. The Journal of cell biology. 2017 216:2179-2199. (IHC; Mouse)
TRPV4 Does Not Regulate the Distal Retinal Light Response. Yarishkin O, Phuong TTT, Lakk M, Križaj D. Advances in experimental medicine and biology. 2018 1074:553-560.
The expression and function of TRPV4 channels in primate retinal ganglion cells and bipolar cells. Gao F, Yang Z, Jacoby RA, Wu SM, Pang JJ. Cell death & disease. 2019 May;10:364.
Immunocytochemical Profiling of Cultured Mouse Primary Retinal Cells. Marina C Zalis, Sebastian Johansson, Ulrica Englund-Johansson. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2017 Apr;65:223-239.
Mechanisms underlying selective coupling of endothelial Ca 2+<sup> signals with eNOS vs. IK/SK channels in systemic and pulmonary arteries. Matteo Ottolini , Zdravka Daneva, Yen-Lin Chen, Eric L Cope, Ramesh B Kasetti, Gulab S Zode, Swapnil K Sonkusare. The Journal of physiology. 2020 Sep;;598:3577-3596.
Generators of Pressure-Evoked Currents in Vertebrate Outer Retinal Neurons. Ji-Jie Pang, Fan Gao, Samuel M Wu. Cells. 2021 May;10:1288.
Endothelial pannexin 1-TRPV4 channel signaling lowers pulmonary arterial pressure in mice. Zdravka Daneva, Matteo Ottolini , Yen Lin Chen, Eliska Klimentova, Maniselvan Kuppusamy, Soham A Shah, Richard D Minshall, Cheikh I Seye, Victor E Laubach, Brant E Isakson, Swapnil K Sonkusare. eLife. 2021 Sep;10:e67777.
Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1. Trine L Toft-Bertelsen, Dagne Barbuskaite, Eva Kjer Heerfordt, Sara Diana Lolansen, Søren Norge Andreassen, Nina Rostgaard, Markus Harboe Olsen, Nicolas H Norager, Tenna Capion, Martin Fredensborg Rath, Marianne Juhler, Nanna MacAulay. Fluids and barriers of the CNS. 2022 September;19:69.
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Featured Products
Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig
Applications:
IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Mouse, Human, Rat
Applications:
IHC, Western blot
Reactivity:
Human
Range:
3.12-200 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
