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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-C94498-100 100 µl (1 mg/ml) $325 
Antibody

Polyclonal Rabbit anti‑Mouse TRPV4 Antibody (aa100‑150, IHC, IF, WB) LS‑C94498

Polyclonal Rabbit anti‑Mouse TRPV4 Antibody (aa100‑150, IHC, IF, WB) LS‑C94498

Antibody:
Rabbit Polyclonal to Mouse TRPV4
Application:
IHC, IHC-Fr, IF, WB
Reactivity:
Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$325 
LS-C94498-100
100 µl
1 mg/ml
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Mouse TRPV4
Application:
IHC, IHC-Fr, IF, WB
Reactivity:
Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
TRPV4 antibody LS-C94498 is an unconjugated rabbit polyclonal antibody to TRPV4 (aa100-150) from mouse. It is reactive with mouse and rat. Validated for IF, IHC and WB. Cited in 6 publications.
Target
Mouse TRPV4
Synonyms
TRPV4 | CMT2C | HMSN2C | OTRPC4 | SSQTL1 | VR-OAC | VRL-2 | Osm-9-like TRP channel 4 | SPSMA | TRP12 | VRL2 | VROAC | SMAL
Host
Rabbit
Reactivity
Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Immunofluorescence
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide from 1t cytoplasmic domain of mouse TRPV4 conjugated to an immunogenic carrier protein.
Epitope
aa100-150
Specificity
Specific for TRPV4.
Usage
IHC: Antigen retrieval is essential for use on paraffin sections.
Presentation
Lyophilized
Reconstitution
100 µl Sterile water
Storage
Maintain lyophilized and reconstituted antibodies at -20°C for long term storage and at 2°C to 8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TRPV4
Q9HBA0 NM_021625 NP_067638.3

LSBio Ratings

TRPV4 Antibody (aa100-150) for IHC, IF/Immunofluorescence, WB/Western LS-C94498 has an LSBio Rating of
Publications (4.5)

Publications (6)

The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells. Ryskamp DA, Witkovsky P, Barabas P, Huang W, Koehler C, Akimov NP, Lee SH, Chauhan S, Xing W, Rentera RC, Liedtke W, Krizaj D. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 31:7089-101. (WB, IHC-Fr; Mouse, Human)

Neurite outgrowth and synaptophysin expression of postnatal CNS neurons on GaP nanowire arrays in long-term retinal cell culture. Piret G, Perez MT, Prinz CN. Biomaterials. 2013 34:875-87. (ICC, IHC-Fr; Mouse)

Dual contribution of TRPV4 antagonism in the regulatory effect of vasoinhibins on blood-retinal barrier permeability: diabetic milieu makes a difference. Arredondo Zamarripa D, Noguez Imm R, Bautista Cortés AM, Vázquez Ruíz O, Bernardini M, Fiorio Pla A, Gkika D, Prevarskaya N, López-Casillas F, Liedtke W, Clapp C, Thébault S. Scientific reports. 2017 7:13094. (IHC; Rat)

Polarity of varicosity initiation in central neuron mechanosensation. Gu Y, Jukkola P, Wang Q, Esparza T, Zhao Y, Brody D, Gu C,. The Journal of cell biology. 2017 216:2179-2199. (IHC; Mouse)

TRPV4 Does Not Regulate the Distal Retinal Light Response. Yarishkin O, Phuong TTT, Lakk M, Križaj D. Advances in experimental medicine and biology. 2018 1074:553-560.

The expression and function of TRPV4 channels in primate retinal ganglion cells and bipolar cells. Gao F, Yang Z, Jacoby RA, Wu SM, Pang JJ. Cell death & disease. 2019 May;10:364.

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Requested From: United States
Date Requested: 7/3/2020