Target
Human TP73 / p73
Synonyms
TP73 | p53-like transcription factor | p73 | p53-related protein | Tumor protein p73
Reactivity
Human
(tested or 100% immunogen sequence identity)
Immunogen
Full-length human p73. IMG-260 reacts with an epitope that is located on the C-Terminus of human p73 only. It does not cross react with mouse p73 or with p53.
Specificity
Caspase-cleaved p73 fragments, including 55 kD and 45 kD, have been described (Sayan et al, 2008). The ability to recognize a p73 fragment will depend on whether or not epitope is contained in the fragment. It does not cross react with mouse p73 or with p53.