Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TP73, p53-like transcription factor, p73, p53-related protein, Tumor protein p73
(tested or 100% immunogen sequence identity)
Protein G purified
Western blot (1:500)
TP73 / p73 antibody was raised against full-length human p73. IMG-260 reacts with an epitope that is located on the C-terminal region of human p73 only. It does not cross react with mouse p73 or with p53.
Caspase-cleaved p73 fragments, including 55 kD and 45 kD, have been described (Sayan et al, 2008). The ability to recognize a p73 fragment will depend on whether or not epitope is contained in the fragment. It does not cross react with mouse p73 or with p53.
This gene encodes tumor protein p73, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73 and have high sequence similarity to one another, which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis.