Human TP63 / p63

Rabbit

Human, Mouse (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Protein A purified

Azide-free, BSA-free. Also available Unmodified or Ready-to-Use.

Amino acids ENNAQTQFSEPQY (aa 5-17) of human p40 / p63 delta were used as the immunogen for this antibody. Percent identity by BLAST analysis: Human, Mouse, Ferret, Sheep, Rabbit (100%); Rat (92%); Turkey, Chicken, Xenopus (85%).

aa5-17

Human TP63 / p63

• IHC - Paraffin (1 - 2 µg/ml)
• Western blot (0.5 - 1 µg/ml)

p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p40 antibody's ability to distinguish between the tumor types appears to be superior when compared to p63. The ability to utilize a p40 antibody probe as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques.

1X PBS

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q9H3D4 NCBI: NM_003722 NP_003713.3