Monoclonal Mouse anti‑Human TNRC9 / TOX3 Antibody (clone TOX3/1124, Azide‑free,BSA‑free, aa200‑400, IHC, IF, WB) LS‑C390211
Monoclonal Mouse anti‑Human TNRC9 / TOX3 Antibody (clone TOX3/1124, Azide‑free,BSA‑free, aa200‑400, IHC, IF, WB) LS‑C390211
Antibody:
TNRC9 / TOX3 Mouse anti-Human Monoclonal (aa200-400) (Azide-free, BSA-free) (TOX3/1124) Antibody
Application:
IHC, IF, WB, Flo
Format:
Unconjugated, Azide-free, BSA-free
Overview
Antibody:
TNRC9 / TOX3 Mouse anti-Human Monoclonal (aa200-400) (Azide-free, BSA-free) (TOX3/1124) Antibody
Application:
IHC, IF, WB, Flo
Format:
Unconjugated, Azide-free, BSA-free
Specifications
Description
TOX3 antibody LS-C390211 is an unconjugated mouse monoclonal antibody to human TOX3 (TNRC9) (aa200-400). Validated for Flow, IF, IHC and WB.
Target
Human TNRC9 / TOX3
Synonyms
TOX3 | CAGF9 | TNRC9
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free, BSA-free.
Also available
Unmodified or
Ready-to-Use.
Immunogen
Recombinant fragment (139 amino acid residues around aa200-400) from the human protein.
Specificity
Human TNRC9 / TOX3
Applications
- IHC
- Immunofluorescence (0.5 - 1 µg/ml)
- Western blot (0.5 - 1 µg/ml)
- Flow Cytometry (0.5 - 1 µg/10E6 cells)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. It recognizes an ~63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts. Optimal dilution of the TOX-3 antibody should be determined by the researcher.
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human
Applications:
IHC, Immunofluorescence, Western blot, Flow Cytometry
Reactivity:
Human
Range:
13.72-10000 pg/ml
Species:
Hepatitis B Virus
Applications:
ELISA
Reactivity:
Porcine
Range:
0.31-20 ng/ml
Species:
Human, Mouse, Rat
Applications:
IHC - Paraffin, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/25/2024