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TNNI3 / Cardiac Troponin I
troponin I type 3 (cardiac)
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
| Gene Name: | troponin I type 3 (cardiac) |
| Synonyms: | TNNI3, CTnI, CMD1FF, CMD2A, RCM1, Troponin I, cardiac, Troponin I, cardiac muscle, Troponin I type 3 (cardiac), Cardiac troponin I, CMH7 |
| Target Sequences: | NM_000363 NP_000354.4 P19429 |
Publications (5)
1
Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance. Kirthana Ganeshan, Joni Nikkanen, Kevin Man, Yew Ann Leong, Yoshitaka Sogawa, J Alan Maschek, Tyler Van Ry, D Nyasha Chagwedera, James E Cox, Ajay Chawla. Cell. 2019 April;177:399-413.e12. [Full Text Article]
[PubMed:30853215]
[PMC:PMC6456449]
2
MR-guided pulsed focused ultrasound improves mesenchymal stromal cell homing to the myocardium. Kee W Jang, Tsang-Wei Tu, Robert B Rosenblatt, Scott R Burks, Joseph A Frank. Journal of cellular and molecular medicine. 2020 October; [Full Text Article]
[PubMed:33067927]
[PMC:PMC7701528]
3
Assessment of inflammatory markers and mitochondrial factors in a rat model of sepsis-induced myocardial dysfunction. Xiao-Mei Zeng, De-Hong Liu, Yong Han, Zhi-Qiang Huang, Ji-Wen Zhang, Qun Huang. American journal of translational research. 2020 April;12:901-911.
[PubMed:32269722]
[PMC:PMC7137057]
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TNNI3 / Cardiac Troponin I Mouse anti-Bovine Monoclonal Antibody
Frog, Chicken, Bovine, Rabbit, Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$575
Cancer
TNNI3 / Cardiac Troponin I Goat anti-Human Polyclonal (aa27-40) Antibody
Human
ELISA, IHC-P
Unconjugated
0.25 mg/$565
TNNI3 / Cardiac Troponin I Goat anti-Human Polyclonal (aa117-127) Antibody
Mouse, Dog, Bovine, Rat, Pig, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µg/$503
TNNI3 / Cardiac Troponin I Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
1 mg/$1,139
Sandwich
96-Well Strip Plate
Pig
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$1,100
E. coli
His, N-Terminal
25.8 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
Sandwich
96-Well Microplate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
Sandwich
96-Well Microplate
Mouse
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
Sandwich
96-Well Strip Plate
Mouse
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Sandwich CLIA
96-Well Strip Plate
Human
2.74 - 2000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$968
Sandwich
96-Well Strip Plate
Pig
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$889
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$685
Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
Sandwich
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
TNNI3 / Cardiac Troponin I Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, IHC, IP, WB
HRP Conjugated
100 µl/$1,094
TNNI3 / Cardiac Troponin I Rabbit anti-Mouse Polyclonal (aa2-211) Antibody
Mouse, Rat
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Sandwich
96-Well Strip Plate
Dog
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$685
TNNI3 / Cardiac Troponin I Chicken anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
1 mg/$469
E. coli
6His, N-terminus
26 kDa
1 mg/$2,029; 10 µg/$253; 50 µg/$308
Sandwich
96-Well Microplate
Human
0.38 - 625 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
TNNI3 / Cardiac Troponin I Mouse anti-Human Monoclonal (1E7) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
TNNI3 / Cardiac Troponin I Mouse anti-Human Monoclonal (aa190-196) (MF4) Antibody
Human
IHC, IP, WB
Unconjugated
0.2 mg/$459; 0.5 mg/$555
TNNI3 / Cardiac Troponin I Mouse anti-Human Monoclonal Antibody
Fish, Pig, Rat, Rabbit, Mouse, Goat, Dog, Bovine, Human, Monkey
ELISA, WB
Unconjugated
50 µg/$316; 100 µg/$386
TNNI3 / Cardiac Troponin I Mouse anti-Human Monoclonal (M18) Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
1 mg/$811
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