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TNIK

TRAF2 and NCK interacting kinase

Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.

Gene Name: TRAF2 and NCK interacting kinase
Family/Subfamily: Protein Kinase , MSN
Synonyms: TNIK, ZC2, KIAA0551
Target Sequences: NM_015028 BAA25477.2 Q9UKE5

☰ Filters
Antibodies (36)
Proteins (4)
Over-Expression Lysate (2)
Primary (36)
Recombinant (2)
TNIK (40)
Human (35)
Mouse (15)
Rat (4)
Bat (6)
Bovine (5)
Chicken (1)
Dog (5)
Gibbon (3)
Guinea pig (3)
Hamster (1)
Horse (5)
Monkey (7)
Rabbit (6)
IHC (18)
IHC-P (6)
WB (21)
ELISA (26)
ICC (1)
IF (1)
IP (2)
Peptide-ELISA (1)
rabbit (36)
Product Group
IHCPlus (3)
PathPlus Cancer (1)
IgG (26)
polyclonal pc (36)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (15)
aa1-30 (7)
C-Terminus (6)
Ser764 (6)
Internal (4)
aa921-970 (4)
aa600-650 (1)
aa750-800 (1)
No (40)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
TNIK Antibody - Anti-TNIK antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
Fast Shipping
TNIK Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Bovine, Rat, Hamster, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
TNIK Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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TNIK Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
TNIK Antibody - TNIK antibody Western blot of Mouse Spleen lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNIK Rabbit anti-Mouse Polyclonal (aa921-970) Antibody
Mouse
WB
Unconjugated
100 µl/$424
TNIK Antibody - Anti-TNIK antibody IHC of human skeletal muscle, myocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
TNIK Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Dog, Bovine, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
TNIK Antibody - Anti-TNIK antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
TNIK Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
TNIK Antibody - Anti-TNIK antibody IHC of human skeletal muscle, myocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
TNIK Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Bat, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
TNIK Antibody - Immunohistochemistry of paraffin-embedded human appendix tissue at dilution of 1:100
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TNIK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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TNIK Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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TNIK Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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TNIK Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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TNIK Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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TNIK Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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TNIK Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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TNIK Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$734
Select
TNIK Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$952
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TNIK Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$952
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TNIK Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$952
Select
TNIK Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated, Azide-free
200 µl/$952
Select
TNIK Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$952
Select
TNIK Rabbit anti-Human Polyclonal (Ser764) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
TNIK Rabbit anti-Human Polyclonal (Ser764) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
TNIK Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
TNIK Antibody - All lanes: Anti-TNIK (S764) Antibody at 1:500 dilution Lane 1: Human brain lysate Lane 2: Caco2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 155 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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TNIK Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$393
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TNIK Rabbit anti-Human Polyclonal (aa600-650) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
TNIK Antibody - Western blot analysis of TNIK using K562 whole cells lysates
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TNIK Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 40 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).