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Catalog Number	Size	Price
LS-C751494-20	20 µg (200 µg/ml)	$371
LS-C751494-100	100 µg (200 µg/ml)	$574

TNFSF15 / TL1A / VEGI Antibody - Formalin-fixed, paraffin-embedded human Spleen stained with TNFS15 / VEGI Monoclonal Antibody (rVEGI /1283).

TNFSF15 / TL1A / VEGI Antibody - Formalin-fixed, paraffin-embedded human Parathyroid Mass stained with TNFS15 / VEGI Monoclonal Antibody (rVEGI /1283).

TNFSF15 / TL1A / VEGI Antibody - Analysis of Protein Array containing more than 19,000 full-length human proteins using TNFS15 / VEGI Recombinant Mouse Monoclonal Antibody (rVEGI/1283).Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

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Recombinant Monoclonal Mouse anti‑Human TNFSF15 / TL1A / VEGI Antibody (clone rVEGI/1283, IHC) LS‑C751494

Name: Anti-TNFSF15 / TL1A / VEGI Antibody | Mouse anti-Human IHC | LSBio
Brand: Lifespan BioSciences
SKU: LS-C751494-20
Price: 371.0000 USD
Availability: InStock

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Antibody:

TNFSF15 / TL1A / VEGI Mouse anti-Human Recombinant Monoclonal (rVEGI/1283) Antibody

Application:

IHC-P

Reactivity:

Human

Format:

Unconjugated, Unmodified

Other formats:

Azide-free, Carrier-free

$371

LS-C751494-20

Toll Free North America

206-374-1102

For Research Use Only

Specifications Validation Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

TNFSF15 / TL1A / VEGI Mouse anti-Human Recombinant Monoclonal (rVEGI/1283) Antibody

Application:

IHC-P

Reactivity:

Human

Format:

Unconjugated, Unmodified

Other formats:

Azide-free, Carrier-free

Specifications

Description

VEGI antibody LS-C751494 is an unconjugated mouse recombinant monoclonal antibody to human VEGI (TNFSF15 / TL1A). Validated for IHC.

Target

Human TNFSF15 / TL1A / VEGI

Synonyms

See All TNFSF15 / TL1A / VEGI Antibodies

Host

Mouse

Reactivity

Human (tested or 100% immunogen sequence identity)

Clonality

IgG1,k Recombinant Monoclonal

Clone

rVEGI/1283

Conjugations

Unconjugated

Purification

Protein A/G purified

Modifications

Unmodified. Also available Azide-free, Carrier-free.

Immunogen

Recombinant full-length human VEGI protein. Antigen Molecular Weight: 22 kDa

Specificity

VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.

Applications

IHC - Paraffin (1 - 2 µg/ml)

Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.

Usage

Immunohistology (Formalin-fixed - 1-2 ug/ml for 30 minutes at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.

Presentation

10 mM PBS, 0.05% BSA, 0.05% Sodium Azide

Storage

Store at 2°C to 8°C for up to 2 years.

Restrictions

For research use only. Intended for use by laboratory professionals.

Guarantee

This antibody carries the LSBio 100% Guarantee.

LSBio Guarantee

About TNFSF15 / TL1A / VEGI

Uniprot: O95150 NCBI: NM_005118 NP_005109.2