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TNFSF13 / APRIL
tumor necrosis factor (ligand) superfamily, member 13
TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
| Gene Name: | tumor necrosis factor (ligand) superfamily, member 13 |
| Family/Subfamily: | TNF , not assigned-TNF |
| Synonyms: | TNFSF13, APRIL, CD256, CD256 antigen, TALL-2, TALL2, ZTNF2, TNF-related death ligand 1, TRDL-1, UNQ383/PRO715 |
| Target Sequences: | NM_003808 NP_003799.1 O75888 |
Publications (3)
1
Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia. Robak OH, Heimesaat MM, Kruglov AA, Prepens S, Ninnemann J, Gutbier B, Reppe K, Hochrein H, Suter M, Kirschning CJ, Marathe V, Buer J, Hornef MW, Schnare M, Schneider P, Witzenrath M, Bereswill S, Steinhoff U, Suttorp N, Sander LE, Chaput C, Opitz B. The Journal of clinical investigation. 2018 August;128:3535-3545. [Full Text Article]
[PubMed:29771684]
[PMC:PMC6063483]
2
Soluble a-proliferation-inducing ligand (sAPRIL), a novel serum biomarker predicting the recurrence and metastasis of pancreatic adenocarcinoma after surgery. Han L, Zhang W, Song F, Guo Y, Guo K, Zhou W. Molecular medicine reports. 2014 October;10:1978-1984. [Full Text Article]
[PubMed:25110120]
3
Development and characterization of APRIL antagonistic monoclonal antibodies for treatment of B-cell lymphomas. Guadagnoli M, Kimberley FC, Phan U, Cameron K, Vink PM, Rodermond H, Eldering E, Kater AP, van Eenennaam H, Medema JP. Blood. 2011 Jun;117:6856-65. [Full Text Article]
[PubMed:21543761]
Related Antibodies: LS-C18659, LS-C18687, LS-C18658.
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TNFSF13 / APRIL
(138)
Reactivity
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(65)
Mouse
(38)
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(32)
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(134)
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(2)
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(3)
TNFSF13 / APRIL Mouse anti-Human Monoclonal (aa93-233) (Aprily-8) Antibody
Human
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$530
TNFSF13 / APRIL Rabbit anti-Human Polyclonal (aa151-200) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
TNFSF13 / APRIL Mouse anti-Human Monoclonal (aa93-233) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$563
TNFSF13 / APRIL Rabbit anti-Human Polyclonal (aa1-17) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$440
TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$818
Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$783
Sandwich
96-Well Microplate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
TNFSF13 / APRIL Mouse anti-Human Monoclonal (Aprily-1) Antibody
Human
Flo, IP, WB
Unconjugated
100 µg/$538
TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
Sandwich
96-Well Strip Plate
Human
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
TNFSF13 / APRIL Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
High Five Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
16.3 kDa
2 µg/$268; 10 µg/$349
TNFSF13 / APRIL Rat anti-Human Monoclonal (aa105-250) Antibody
Mouse, Human
ELISA, Flo, ICC
Unconjugated
100 µg/$550
TNFSF13 / APRIL Mouse anti-Human Monoclonal (4A11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
E. coli
His
19.4 kDa
10 µg/$295; 50 µg/$532; 100 µg/$850; 200 µg/$1,049; 1 mg/$2,215; 500 µg/$1,733; 5 mg/$3,711; 2 mg/$2,407
Competitive EIA
96-Well Strip Plate
Mouse
5 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$460; 100 µg/$584
TNFSF13 / APRIL Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
TNFSF13 / APRIL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
TNFSF13 / APRIL Rabbit anti-Mouse Polyclonal (aa96-241) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317
TNFSF13 / APRIL Rabbit anti-Human Polyclonal (aa105-247) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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product results
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