Human TNFRSF25 / DR3
TNFRSF25 | APO-3 | APO3 | DDR3 | Death receptor 3 | DR3 | Death receptor beta | LARD | Protein WSL | TR3 | WSL | WSL-1 | WSL-LR | Apoptosis inducing receptor | TNFRSF12 | WSL1 | Protein WSL-1 | TRAMP
(tested or 100% immunogen sequence identity)
Peptide sequence QGGTRSPRCDCAGDFH from N-Terminus of human DR3 . Percent identity by BLAST analysis: Human (100%); Gorilla, Monkey (94%); Gibbon (88%).
Recognizes a 59kD apoptosis related protein designated DR3 (death receptor-3). DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95). The ligand for DR3 has very recently been identified and has been termed Apo-3L. DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, and functionally induces apoptosis and NF-KB activation.