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TNFRSF1B / TNFR2
tumor necrosis factor receptor superfamily, member 1B
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
| Gene Name: | tumor necrosis factor receptor superfamily, member 1B |
| Family/Subfamily: | TNF Receptor , not assigned-TNF Receptor |
| Synonyms: | TNFRSF1B, CD120b antigen, CD120b, p75 TNF receptor, Soluble TNFR1B variant 1, TNFBR, Tumor necrosis factor receptor, TNF-R-II, TNF-R75, TNFR2, p75TNFR, p80 TNF-alpha receptor, TBPII, TNF-R2, TNFR80, TNF-RII, TNFR-II, TNFR1B |
| Target Sequences: | NM_001066 NP_001057.1 P20333 |
Publications (1)
1
Selective inhibition of soluble tumor necrosis factor signaling reduces abdominal aortic aneurysm progression. Silke Griepke, Emilie Grupe, Jes Sanddal Lindholt, Elizabeth Hvitfeldt Fuglsang, Lasse Bach Steffensen, Hans Christian Beck, Mia Dupont Larsen, Sissel Karoline Bang-Møller, Martin Overgaard, Lars Melholt Rasmussen, Kate Lykke Lambertsen, Jane Stubbe. Frontiers in cardiovascular medicine. 2022 October;9:942342. [Full Text Article]
[PubMed:36186984]
[PMC:PMC9523116]
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TNFRSF1B / TNFR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
TNFRSF1B / TNFR2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
TNFRSF1B / TNFR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
TNFRSF1B / TNFR2 Mouse anti-Human Monoclonal (MR2-1) Antibody
Human, Monkey, Cynomolgus
Flo, Func, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$652
TNFRSF1B / TNFR2 Mouse anti-Human Monoclonal (FITC) (MR2-1) Antibody
Human, Monkey, Cynomolgus
Flo, Func, IHC, IHC-Fr, IP, WB
FITC Conjugated
100 µg/$738
TNFRSF1B / TNFR2 Mouse anti-Human Monoclonal (aa23-257) (22221 (2/220)) Antibody
Human
ELISA, IHC, IHC-Fr, WB
Unconjugated
0.1 mg/$432
TNFRSF1B / TNFR2 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µg/$450; 500 µg/$950
TNFRSF1B / TNFR2 Rabbit anti-Human Polyclonal (aa102-151) Antibody
Human
WB
Unconjugated
100 µl/$424
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$870
TNFRSF1B / TNFR2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
TNFRSF1B / TNFR2 Rat anti-Mouse Monoclonal (HM102) Antibody
Mouse
ELISA, Flo, IHC, IHC-Fr, IP
Unconjugated
1 ml/$801
TNFRSF1B / TNFR2 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-Fr, WB
Unconjugated
100 µg/$672
TNFRSF1B / TNFR2 Rabbit anti-Cynomolgus Polyclonal Antibody
Cynomolgus
ELISA
Unconjugated
100 µl/$412
TNFRSF1B / TNFR2 Mouse anti-Human Monoclonal (80M2) Antibody
Rat, Human
Flo, Func, IF, IP
Unconjugated
100 µg/$652
TNFRSF1B / TNFR2 Rabbit anti-Human Polyclonal (aa103-121) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
TNFRSF1B / TNFR2 Rabbit anti-Mouse Monoclonal (Preservative Free) (R204) Antibody
Mouse
Block, ELISA, Neut
Unconjugated, Preservative Free
200 µg/$361; 500 µg/$436
TNFRSF1B / TNFR2 Rabbit anti-Mouse Monoclonal (Preservative Free) (340) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
TNFRSF1B / TNFR2 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$1,129
TNFRSF1B / TNFR2 Mouse anti-Human Monoclonal (Concentrated) (80M2) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated, Concentrated
1 ml/$786
TNFRSF1B / TNFR2 Rat anti-Mouse Monoclonal (FITC) Antibody
Mouse
ELISA, Flo, IHC, IHC-Fr
FITC Conjugated
100 µg/$958
TNFRSF1B / TNFR2 Mouse anti-Human Monoclonal Antibody
Human, Monkey
ELISA, Flo, IP, WB
Unconjugated
100 µg/$919
TNFRSF1B / TNFR2 Rabbit anti-Mouse Polyclonal (aa296-324) Antibody
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
TNFRSF1B / TNFR2 Goat anti-Mouse Polyclonal (aa65-78) Antibody
Mouse, Rat
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
TNFRSF1B / TNFR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
TNFRSF1B / TNFR2 Rat anti-Mouse Monoclonal (Biotin) (HM102) Antibody
Mouse
Flo, IHC, IHC-Fr
Biotin Conjugated
50 µg/$508
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