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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNFRSF12A / TWEAK Receptor Antibody (aa104‑118) LS‑C837
TWEAK Receptor antibody LS-C837 is an unconjugated rabbit polyclonal antibody to TWEAK Receptor (TNFRSF12A) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C837-100
100 µg (0.5 mg/ml)
$335

Popular TNFRSF12A / TWEAK Receptor Products

Staining of human Fn14 transfected L5178Y cells with 0.5 ug of purified mouse IgG2b isotype control (open histogram) or 0.5 ug purified anti-Fn14 (ITEM-4) (colored histogram) followed by FITC anti-mouse IgG. Total viable cells were analyzed.
Species: Human
Applications: IHC, IHC - Frozen, Western blot, Flow Cytometry
Anti-TWEAKR antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B605 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Antibody
Species: Human, Mouse
Applications: IHC, IHC - Frozen, Western blot, Flow Cytometry

Product Description

TWEAK Receptor antibody LS-C837 is an unconjugated rabbit polyclonal antibody to TWEAK Receptor (TNFRSF12A) from human, mouse, rat and other species. Validated for WB.

Specifications

Target
Human TNFRSF12A / TWEAK Receptor
Synonyms
TNFRSF12A, CD266 antigen, CD266, FGF-inducible 14, FN14, Tweak-receptor, TWEAKR
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
Immunogen
This antibody was developed against a synthetic peptide containing amino acids 106-118 (C-RREKFTTPIEETG) of human TweakR. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Platypus (100%); Opossum (92%); Xenopus (85%).
Epitope
aa104-118
Specificity
A synthetic peptide containing amino acids 104-118 of human TweakR.
Presentation
PBS, 0.05% Sodium Azide, 0.05% BSA
Storage
Short term: 4°C; Long term: -70°C.
Restrictions
For research use only.
About TNFRSF12A / TWEAK Receptor
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. Q9NP84 NM_016639 NP_057723.1


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Images

Western blot

Western blot of TweakR in A) human liver lysate, B) mouse liver tissue lysate, and C) rat liver lysate using antibody at 1:500.
Western blot of TweakR in A) human liver lysate, B) mouse liver tissue lysate, and C) rat liver lysate using antibody at 1:500.

Western blot

Western blot of TweakR in 293 cells. Untransfected (lane 1) or transfected with human TweakR (lane 2).
Western blot of TweakR in 293 cells. Untransfected (lane 1) or transfected with human TweakR (lane 2).

Western blot

Western blot of TweakR in A) human liver lysate, B) mouse liver tissue lysate, and C) rat liver lysate using antibody at 1:500.
Western blot of TweakR in A) human liver lysate, B) mouse liver tissue lysate, and C) rat liver lysate using antibody at 1:500.

Western blot

Western blot of TweakR in 293 cells. Untransfected (lane 1) or transfected with human TweakR (lane 2).
Western blot of TweakR in 293 cells. Untransfected (lane 1) or transfected with human TweakR (lane 2).

Western blot

Western blot of TweakR in A) human liver lysate, B) mouse liver tissue lysate, and C) rat liver lysate using antibody at 1:500.
Western blot of TweakR in A) human liver lysate, B) mouse liver tissue lysate, and C) rat liver lysate using antibody at 1:500.

Western blot

Western blot of TweakR in 293 cells. Untransfected (lane 1) or transfected with human TweakR (lane 2).
Western blot of TweakR in 293 cells. Untransfected (lane 1) or transfected with human TweakR (lane 2).

Western blot

Western blot of TweakR in A) human liver lysate, B) mouse liver tissue lysate, and C) rat liver lysate using antibody at 1:500.
Western blot of TweakR in A) human liver lysate, B) mouse liver tissue lysate, and C) rat liver lysate using antibody at 1:500.

Western blot

Western blot of TweakR in 293 cells. Untransfected (lane 1) or transfected with human TweakR (lane 2).
Western blot of TweakR in 293 cells. Untransfected (lane 1) or transfected with human TweakR (lane 2).

Requested From: United States
Date Requested: 10/15/2018

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