TMPRSS2 / Epitheliasin

transmembrane protease, serine 2

Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, proteolytic cleavage of ACE2, which might promote viral uptake, and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry. Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) , human coronavirus EMC (HCoV-EMC), SARS-CoV and SARS-CoV-2, and the fusion glycoproteins F0 of Sendai virus (SeV), human metapneumovirus (HMPV), human parainfluenza 1, 2, 3, 4a and 4b viruses (HPIV). Essential for spread and pathogenesis of influenza A virus (strains H1N1, H3N2 and H7N9); involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity.

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Products

Antibodies (37)

ELISA Kits (10)

Proteins (7)

Type

Over-Expression Lysate (2)

Primary (37)

Recombinant (5)

Sandwich (9)

Sandwich CLIA (1)

Target

TMPRSS2 / Epitheliasin (54)

Reactivity

Human (31)

Mouse (18)

Rat (6)

Bovine (3)

Chicken (1)

Guinea pig (1)

Monkey (1)

Pig (3)

Porcine (1)

Rabbit (4)

Application

IHC (6)

IHC-P (6)

WB (34)

Flo (1)

ELISA (2)

Peptide-ELISA (2)

Host

rabbit (35)

mouse (1)

goat (1)

Product Group

Antibodies to Coronavirus-Associated Targets (34)

Coronavirus Antibodies Proteins cDNAs (42)

Coronavirus Detection (10)

ELISA Kits for Associated Targets (10)

IHCPlus (5)

SARS-CoV-2 Associated Proteins (7)

Isotype

IgG (6)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (36)

Clone

2F4 (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (8)

APC (2)

APC Conjugated (2)

Biotin Conjugated (4)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (17)

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Epitope

aa254-490 (8)

aa284-492 (8)

C-Terminus (4)

N-Terminus (4)

Internal Region (1)

aa100-470 (1)

aa314-343 (1)

Publications

No (52)

Yes (2)

Sample Type

Cell Lysates (1)

Plasma (5)

Serum (5)

Tissue Homogenates (3)

Tag

6His, N-terminus (1)

GST, N-terminus (2)

His,N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (1)

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IHC-plus™ TMPRSS2 / Epitheliasin Antibody LS-B14876

(4.0) Rating

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

TMPRSS2 / Epitheliasin Antibody (aa314-343) LS-C100564

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Human Polyclonal (aa314-343) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

400 µl/$393

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Human TMPRSS2 / Epitheliasin Protein (Recombinant 6His, N-terminus) (aa106-492) - LS-G57269

(4.2) Rating

(3) Publication(s)

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Human TMPRSS2 / Epitheliasin (Sandwich ELISA) ELISA Kit - LS-F21097

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human TMPRSS2 / Epitheliasin Protein (Recombinant GST, N-terminus) (Full Length) - LS-G30729

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Molecular Weight:

79.86 kDa

Price:

2 µg/$439

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TMPRSS2 / Epitheliasin Antibody (aa254-490) LS-C373022

(4.0) Rating

(1) Publication(s)

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Mouse Polyclonal (aa254-490) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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TMPRSS2 / Epitheliasin Antibody (aa254-490, PE) LS-C725988

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Mouse Polyclonal (aa254-490) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• PE

• Unconjugated
• PE

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Human TMPRSS2 / Epitheliasin Protein (Recombinant His,N-terminus) (aa284-492) - LS-G15055

Source:

E. coli

Tag:

His,N-terminus

Molecular Weight:

27.2 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

Select

Human TMPRSS2 / Epitheliasin (Sandwich ELISA) ELISA Kit - LS-F6456

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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TMPRSS2 / Epitheliasin Antibody (clone 2F4) LS-C198350

Antibody:

TMPRSS2 / Epitheliasin Mouse anti-Human Monoclonal (2F4) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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TMPRSS2 / Epitheliasin Antibody (C-Terminus, FITC) LS-C449056

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Bovine, Rat, Pig, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

Select

Human TMPRSS2 / Epitheliasin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81791

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.7 kDa

Price:

20 µg/$150

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Mouse TMPRSS2 / Epitheliasin Protein (Recombinant His-T7) (aa254-490) - LS-G25104

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.6 kDa

Price:

10 µg/$282; 50 µg/$447; 100 µg/$715; 200 µg/$892; 1 mg/$2,005; 500 µg/$1,543; 5 mg/$3,123; 2 mg/$2,192

Select

Human TMPRSS2 / Epitheliasin (Sandwich ELISA) ELISA Kit - LS-F35035

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human TMPRSS2 / Epitheliasin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100612

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.7 kDa

Price:

100 µg/$494

Select

IHC-plus™ TMPRSS2 / Epitheliasin Antibody (aa100-470) LS-B14093

(4.0) Rating

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Human Polyclonal (aa100-470) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

TMPRSS2 / Epitheliasin Antibody LS-C661116

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

TMPRSS2 / Epitheliasin Antibody (Internal Region) LS-C87230

Antibody:

TMPRSS2 / Epitheliasin Goat anti-Human Polyclonal (Internal Region) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

TMPRSS2 / Epitheliasin Antibody (aa284-492) LS-C296775

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Human Polyclonal (aa284-492) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

IHC-plus™ TMPRSS2 / Epitheliasin Antibody LS-B14581

(4.0) Rating

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

Human TMPRSS2 / Epitheliasin Protein (Recombinant GST, N-terminus) (aa383-492) - LS-G60381

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human TMPRSS2 / Epitheliasin (CLIA) ELISA Kit - LS-F29905

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

IHC-plus™ TMPRSS2 / Epitheliasin Antibody LS-A13621

Fast Shipping

(4.0) Rating

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Human Polyclonal Antibody

Applications:

IHC-P

Format:

Unconjugated

Price:

50 µg/$440

Select

IHC-plus™ TMPRSS2 / Epitheliasin Antibody LS-A13619

Fast Shipping

(4.0) Rating

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Human Polyclonal Antibody

Applications:

IHC-P

Format:

Unconjugated

Price:

50 µg/$440

Select

TMPRSS2 / Epitheliasin Antibody LS-C342249

Antibody:

TMPRSS2 / Epitheliasin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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