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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TLX1 / HOX11 Antibody (aa163‑191) IHC‑plus™ LS‑B10677
Note: This antibody replaces LS-C161925
HOX11 antibody LS-B10677 is an unconjugated rabbit polyclonal antibody to HOX11 (TLX1) from human and mouse. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B10677-200
200 µl
$425

Popular TLX1 / HOX11 Products

Anti-TLX1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit, Chicken
Applications: IHC, IHC - Paraffin, Western blot
TLX1 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Rabbit, Chicken
Applications: Western blot
Anti-TLX1 / HOX11 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Antibody
Species: Human, Mouse
Applications: Western blot, ELISA

Product Description

HOX11 antibody LS-B10677 is an unconjugated rabbit polyclonal antibody to HOX11 (TLX1) from human and mouse. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.

Specifications

Target
Human TLX1 / HOX11
Synonyms
TLX1, Homeobox protein Hox-11, HOX11, T-cell leukemia homeobox 1, Proto-oncogene TCL-3, TCL3, T-cell leukemia, homeobox 1
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Predicted
Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E1713 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B10677. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa163-191
Specificity
This TLX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the Central region of human TLX1.
Presentation
PBS, 0.09% Sodium Azide
Storage
Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
About TLX1 / HOX11
TLX1 / HOX11 is a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants. P31314 NM_005521 NP_005512.1


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Images

Immunohistochemistry

Anti-TLX1 / HOX11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-TLX1 / HOX11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

Western blot

TLX1 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The TLX1 antibody detected the TLX1 protein (arrow).
TLX1 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The TLX1 antibody detected the TLX1 protein (arrow).

Immunohistochemistry

Anti-TLX1 / HOX11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-TLX1 / HOX11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

Western blot

TLX1 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The TLX1 antibody detected the TLX1 protein (arrow).
TLX1 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The TLX1 antibody detected the TLX1 protein (arrow).

Immunohistochemistry

Anti-TLX1 / HOX11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-TLX1 / HOX11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

Western blot

TLX1 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The TLX1 antibody detected the TLX1 protein (arrow).
TLX1 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The TLX1 antibody detected the TLX1 protein (arrow).

Immunohistochemistry

Anti-TLX1 / HOX11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-TLX1 / HOX11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

Western blot

TLX1 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The TLX1 antibody detected the TLX1 protein (arrow).
TLX1 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The TLX1 antibody detected the TLX1 protein (arrow).

Requested From: United States
Date Requested: 11/13/2018

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