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THOP1 / Thimet Oligopeptidase
thimet oligopeptidase 1
Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
| Gene Name: | thimet oligopeptidase 1 |
| Family/Subfamily: | Protease , Metallopeptidase M3 |
| Synonyms: | THOP1, Endopeptidase 24.15, Endopeptidase 3.4.24.15, EP24.15, MEPD_HUMAN, Metalloendopeptidase 3.4.24.15, MP78, Thimet oligopeptidase, Thimet oligopeptidase 1, TOP |
| Target Sequences: | NM_003249 NP_003240.1 P52888 |
Publications (2)
1
Monoclonal antibodies against the human metalloprotease EC 3.4.24.15 label neurofibrillary tangles in Alzheimer's disease brain. Conn KJ, Pietropaolo M, Ju ST, Abraham CR. Journal of neurochemistry. 1996 66:2011-8.
[PubMed:8780030]
2
Mitosis-dependent protein expression in neuroblastoma cell line N1E-115. Azizi AA, Kang SU, Freilinger A, Gruber-Olipitz M, Chen WQ, Yang JW, Hengstschlger M, Slavc I, Lubec G. Journal of proteome research. 2008 7:3412-22.
[PubMed:18582092]
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THOP1 / Thimet Oligopeptidase
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(33)
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(17)
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(3)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(2)
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(2)
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(1)
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(17)
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(8)
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(48)
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(2)
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(2)
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(2)
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(7)
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(1)
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(1)
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(1)
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(3)
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(2)
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(2)
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Low endotoxin level
(3)
THOP1 / Thimet Oligopeptidase Mouse anti-Human Monoclonal (aa56-72) (4D6) Antibody
Rabbit, Mouse, Rat, Primate, Human
ICC, IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
THOP1 / Thimet Oligopeptidase Mouse anti-Human Monoclonal (aa56-72) (Biotin) (4D6) Antibody
Rabbit, Mouse, Rat, Primate, Human
ICC, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
THOP1 / Thimet Oligopeptidase Mouse anti-Human Monoclonal (aa56-72) (DY650) (4D6) Antibody
Human
ICC, IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
THOP1 / Thimet Oligopeptidase Mouse anti-Human Monoclonal (aa56-72) (DY488) (4D6) Antibody
Human
ICC, IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
THOP1 / Thimet Oligopeptidase Mouse anti-Human Monoclonal (aa56-72) (DY550) (4D6) Antibody
Human
ICC, IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
THOP1 / Thimet Oligopeptidase Mouse anti-Human Monoclonal (OTI2D3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
THOP1 / Thimet Oligopeptidase Mouse anti-Human Monoclonal (Carrier-free) (OTI2D3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
THOP1 / Thimet Oligopeptidase Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IP, WB
Unconjugated
100 µl/$412
THOP1 / Thimet Oligopeptidase Mouse anti-Human Monoclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$884
THOP1 / Thimet Oligopeptidase Mouse anti-Human Monoclonal (aa56-72) Antibody
Human
ICC, WB
Unconjugated
100 µl/$649
THOP1 / Thimet Oligopeptidase Mouse anti-Human Monoclonal (2B4) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$423
THOP1 / Thimet Oligopeptidase Sheep anti-Human Polyclonal (aa1-689) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$896
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
THOP1 / Thimet Oligopeptidase Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$469
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human, Orangutan, Gibbon
WB
FITC Conjugated
100 µl/$469
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal (aa25-75) Antibody
Mouse, Human
WB
Unconjugated
10 µl/$295; 100 µl/$514
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal (aa451-597) Antibody
Mouse, Pig, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
THOP1 / Thimet Oligopeptidase Rabbit anti-Human Polyclonal (aa451-597) (Biotin) Antibody
Mouse, Pig, Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
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