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TFF1 / pS2

trefoil factor 1

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. TFF1, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. The TFF1 gene consists of 3 exons, with exon 2 encoding the trefoil domain. The TFF1, TFF2, and TFF3 genes are located within a 55 kb region, suggesting they evolved from a common ancestor by duplication.

Gene Name: trefoil factor 1
Synonyms: TFF1, BCEI, D21S21, HPS2, PNR-2, Polypeptide P1.A, Protein pS2, PS2, HP1.A, Trefoil factor 1
Target Sequences: NM_003225 NP_003216.1 P04155

Publications (2)

1
Gastric TFF1 Expression from Acute to ChronicHelicobacterInfection. Esposito R, Morello S, Vllahu M, Eletto D, Porta A, Tosco A. Frontiers in cellular and infection microbiology. 2017 October;7:434. (Human) [Full Text Article] [PubMed:29085807] [PMC:PMC5649190] Related Antibodies: LS-C155659.
2
C/EBPa Epigenetically Modulates TFF1 Expression via mC-6 Methylation in the Jejunum Inflammation Induced by a Porcine Coronavirus. Huan Qu, Qiufang Zong, Haifei Wang, Shenglong Wu, Demin Cai, Wenbin Bao. Frontiers in immunology. 2022 June;13:881289. [Full Text Article] [PubMed:35693767] [PMC:PMC9174463] Related Antibodies: LS-C312842.

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Antibodies (79)
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TFF1 / pS2 Antibody - IHC of paraffin-embedded Gastric ca, using Trefoil factor 1 antibody at 1:500 dilution.
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TFF1 / pS2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$450
TFF1 / pS2 Antibody - Anti-PS2 / TFF1 antibody IHC of human colon, goblet cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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Cancer
TFF1 / pS2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$440
TFF1 / pS2 Antibody - TFF1 / PS2 antibody. IHC(P): Rat Intestine Tissue.
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TFF1 / pS2 Rabbit anti-Mouse Polyclonal (aa59-72) Antibody
Mouse, Rat, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
TFF1 / pS2 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
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Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
8.3 kDa
10 µg/$277; 50 µg/$371
TFF1 / pS2 Antibody - Estrogen inducible protein pS2 antibody GE2 immunohistochemistry breast cancer.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TFF1 / pS2 Mouse anti-Human Monoclonal (pSer2) (Ready-to-Use) (GE2) Antibody
Human, Chimpanzee
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Ready-to-Use
7 ml/$574
TFF1 / pS2 Antibody - Estrogen inducible protein pS2 antibody GE2 immunohistochemistry breast cancer.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TFF1 / pS2 Mouse anti-Human Monoclonal (pSer2) (Azide-free, BSA-free) (GE2) Antibody
Human, Chimpanzee
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
TFF1 / pS2 Antibody - TFF1 antibody Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TFF1 / pS2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
TFF1 / pS2 Antibody - Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with Estrogen Inducible Protein pS2 antibody (SPM313).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TFF1 / pS2 Mouse anti-Human Monoclonal (aa57-84) (SPM313) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
TFF1 / pS2 Antibody - Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with Estrogen Inducible Protein pS2 antibody (SPM313).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TFF1 / pS2 Mouse anti-Human Monoclonal (aa57-84) (Azide-free, BSA-free) (SPM313) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
TFF1 / pS2 Antibody - Formalin-fixed, paraffin-embedded human breast carcinoma stained with pS2 antibody (SPM573).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TFF1 / pS2 Mouse anti-Human Monoclonal (aa57-84) (SPM573) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
TFF1 / pS2 Antibody - Formalin-fixed, paraffin-embedded human breast carcinoma stained with pS2 antibody (SPM573).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TFF1 / pS2 Mouse anti-Human Monoclonal (aa57-84) (Azide-free, BSA-free) (SPM573) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
TFF1 / pS2 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
TFF1 / pS2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
TFF1 / pS2 Antibody - Formalin-fixed, paraffin-embedded human breast carcinoma stained with TFF1 antibody.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TFF1 / pS2 Mouse anti-Human Monoclonal (C-Terminus) (TFF1/1091) Antibody
Human, Monkey
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
TFF1 / pS2 Antibody - Formalin-fixed, paraffin-embedded human breast carcinoma stained with TFF1 antibody.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TFF1 / pS2 Mouse anti-Human Monoclonal (C-Terminus) (Azide-free, BSA-free) (TFF1/1091) Antibody
Human, Monkey
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
TFF1 / pS2 Antibody - Formalin-fixed, paraffin-embedded human breast carcinoma stained with TFF1 antibody.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TFF1 / pS2 Mouse anti-Human Monoclonal (C-Terminus) (Ready-to-Use) (TFF1/1091) Antibody
Human, Monkey
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
TFF1 / pS2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$1,150
TFF1 / pS2 Antibody - Human Foveolar Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
TFF1 / pS2 Rabbit anti-Human Recombinant Monoclonal (aa50-100) (TFF1/2969R) Antibody
Human
IHC-P
Unconjugated
100 µg/$525
TFF1 / pS2 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-TFF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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TFF1 / pS2 Mouse anti-Human Monoclonal (aa25-84) (OTI1F5) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
TFF1 / pS2 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-TFF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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TFF1 / pS2 Mouse anti-Human Monoclonal (aa25-84) (OTI1A4) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
TFF1 / pS2 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-TFF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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TFF1 / pS2 Mouse anti-Human Monoclonal (aa25-84) (OTI7B12) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
TFF1 / pS2 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-TFF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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TFF1 / pS2 Mouse anti-Human Monoclonal (aa25-84) (OTI5H5) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
TFF1 / pS2 Antibody - Immunohistochemistry of paraffin-embedded human mammary cancer using TFF1 antibodyat dilution of 1:200 (40x lens).
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TFF1 / pS2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
TFF1 / pS2 Antibody - IHC testing of FFPE ovarian carcinoma with TFF1 antibody (clone BCEIP1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TFF1 / pS2 Mouse anti-Human Monoclonal (C-Terminus) (Azide-free, BSA-free) (BCEIP1) Antibody
Human
IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
TFF1 / pS2 Antibody - IHC testing of FFPE ovarian carcinoma with TFF1 antibody (clone BCEIP1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TFF1 / pS2 Mouse anti-Human Monoclonal (C-Terminus) (Ready-to-Use) (BCEIP1) Antibody
Human
IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
Viewing 1-25 of 116 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).