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Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent transcription. Plays a role in the differentiation of preadipocyte fibroblasts to adipocytes, however, does not seem to play a role in differentiation of myoblasts. Required for the integration of TAF10 in the TAF complex. May be important for survival of cells of the inner cell mass which constitute the pluripotent cell population of the early embryo.
Gene Name: | TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa |
Synonyms: | TAF8, 43, HTAFII43, Protein taube nuss, TBP-associated factor 8, TBP-associated factor TAFII43, TAF, TAF(II)43, TAFII-43, Taube nuss homolog, Taube nuss homolog (mouse), TAFII43, TBN, TBP-associated factor 43 kDa |
Target Sequences: | NP_612639.2 Q7Z7C8 |
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