TAB1

TGF-beta activated kinase 1/MAP3K7 binding protein 1

TAB1 was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

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Products

Antibodies (51)

Proteins (8)

ELISA Kits (3)

Type

Custom (1)

Over-Expression Lysate (4)

Primary (51)

Recombinant (4)

Sandwich (2)

Target

TAB1 (62)

Reactivity

Human (53)

Mouse (17)

Rat (7)

Bovine (2)

Chicken (3)

Chimpanzee (3)

Dog (2)

Gibbon (3)

Monkey (4)

Pig (5)

Rabbit (3)

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Application

IHC (5)

IHC-P (2)

WB (43)

DB (6)

ELISA (22)

ICC (2)

IF (3)

IP (4)

Peptide-ELISA (2)

Host

rabbit (45)

mouse (5)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (30)

Clonality

monoclonal mc (6)

polyclonal pc (45)

Format

96-Well Strip Plate (3)

APC (1)

APC Conjugated (4)

Azide-free (3)

Biotin Conjugated (5)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (4)

Unconjugated (26)

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Epitope

aa189-439 (8)

aa401-430 (7)

aa416-445 (7)

pSer423 (6)

N-Terminus (5)

Pro381 (1)

aa205-504 (1)

aa435-485 (1)

aa485-504 (1)

aa7-159 (1)

Publications

No (62)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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IHC-plus™ TAB1 Antibody LS-B584

(4.0) Rating

Antibody:

TAB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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Human TAB1 Protein (Recombinant His, N-Terminal) (aa189-439) - LS-G16162

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

30.6 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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TAB1 Antibody (aa7-159) LS-C39460

Antibody:

TAB1 Goat anti-Human Polyclonal (aa7-159) Antibody

Reactivity:

Mouse, Human

Applications:

ICC, WB

Format:

Unconjugated

Price:

100 µg/$961

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TAB1 Antibody (Pro381) LS-C39459

Antibody:

TAB1 Rabbit anti-Human Monoclonal (Pro381) Antibody

Reactivity:

Human, Monkey

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$688

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TAB1 Antibody LS-C814129

Antibody:

TAB1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Pig, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$250; 100 µg/$404; 200 µg/$505

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TAB1 Antibody (aa205-504) LS-C377604

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa205-504) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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TAB1 Antibody LS-C334263

Antibody:

TAB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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TAB1 Antibody LS-C806711

Antibody:

TAB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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TAB1 Antibody LS-C405134

Antibody:

TAB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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TAB1 Antibody LS-C814133

Antibody:

TAB1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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TAB1 Antibody (aa416-445) LS-C328835

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa416-445) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

TAB1 Antibody (aa416-445, Biotin) LS-C283345

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa416-445) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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TAB1 Antibody (aa416-445, FITC) LS-C283346

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa416-445) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TAB1 Antibody (aa416-445, APC) LS-C283343

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa416-445) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

TAB1 Antibody (aa416-445, Azide-free, HRP) LS-C283347

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa416-445) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free

Select

TAB1 Antibody (aa401-430) LS-C328834

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa401-430) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

TAB1 Antibody (aa401-430, Biotin) LS-C283340

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa401-430) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

TAB1 Antibody (aa401-430, FITC) LS-C283339

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa401-430) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TAB1 Antibody (aa401-430, APC) LS-C283338

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa401-430) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

TAB1 Antibody (aa401-430, PE) LS-C283341

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa401-430) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

TAB1 Antibody (aa401-430, Azide-free, HRP) LS-C283342

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa401-430) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

TAB1 Antibody (phospho-Ser423) LS-C328831

Antibody:

TAB1 Rabbit anti-Human Polyclonal (pSer423) Antibody

Reactivity:

Human

Applications:

DB, ELISA

Format:

Unconjugated

Price:

200 µl/$734

Select

TAB1 Antibody (aa485-504) LS-C288921

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa485-504) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

TAB1 Antibody (aa435-485) LS-C288920

Antibody:

TAB1 Rabbit anti-Human Polyclonal (aa435-485) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

TAB1 Antibody LS-C804041

Antibody:

TAB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Viewing 1-25 of 62 product results

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