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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-C26331-200 200 µl $785 
Antibody

Monoclonal Mouse anti‑Human Synuclein Alpha + Beta Antibody (Tyr39, IHC, WB) LS‑C26331

Monoclonal Mouse anti‑Human Synuclein Alpha + Beta Antibody (Tyr39, IHC, WB) LS‑C26331

Antibody:
Synuclein Alpha + Beta Mouse anti-Human Monoclonal (Tyr39) Antibody
Application:
IHC, ICC, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$785
LS-C26331-200
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Synuclein Alpha + Beta Mouse anti-Human Monoclonal (Tyr39) Antibody
Application:
IHC, ICC, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Synuclein Alpha + Beta antibody LS-C26331 is an unconjugated mouse monoclonal antibody to human Synuclein Alpha + Beta (Tyr39). Validated for ICC, IHC and WB.
Target
Human Synuclein Alpha + Beta
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Monoclonal
Conjugations
Unconjugated
Purification
Ascites
Modifications
Unmodified
Immunogen
Full-length nitrated recombinant human a-synuclein.
Epitope
Tyr39
Specificity
Recognizes nitrated recombinant a-synuclein at Tyr39, Mr 14.5kD or nitrated b-Synuclein, Mr 17kD. Species cross-reactivity: Human.
Applications
  • IHC
  • ICC
  • Western blot (1:5000 - 1:10000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Western Blot: 1:5000-1:10000 detects a- or b-Synuclein recombinant protein nitrated at Tyr39. Nitrated and unnitrated a-synuclein recombinant protein were resolved by electrophoresis, transferred to nitrocellulose and probed with anti-nitro-a/b-Synuclein (Tyr39) (1:5000 dilution). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. nitrated a-Synuclein (~14.5kD). Note. The detected band at ~30kD represents the formation of o, o' -dityrosine cross-links occurring during nitration with. peroxynitrite. Immunohisto/cytochemistry: Detects nitrated a- and b-synuclein in human tissues.
Presentation
0.05% Sodium Azide
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 1/26/2021