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SYNE1 / Nesprin 1

spectrin repeat containing, nuclear envelope 1

Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. May be involved in the maintenance of nuclear organization and structural integrity. Connects nuclei to the cytoskeleton by interacting with the nuclear envelope and with F-actin in the cytoplasm. May be required for centrosome migration to the apical cell surface during early ciliogenesis.

Gene Name: spectrin repeat containing, nuclear envelope 1
Synonyms: SYNE1, 8B, ARCA1, C6orf98, CPG2, DJ45H2.2, EDMD4, Enaptin, KIAA0796, MYNE1, Nesp1, KIAA1262, KIAA1756, Syne-1, Myne-1, SCAR8, SYNE-1B, Nesprin 1, Nesprin-1
Target Sequences: AY061755 AAL33798.1 Q8NF91

☰ Filters
Antibodies (17)
Proteins (2)
ELISA Kits (1)
Primary (17)
Recombinant (2)
Sandwich (1)
SYNE1 / Nesprin 1 (20)
Human (18)
Mouse (2)
Rat (1)
Rabbit (1)
IHC (2)
IHC-P (1)
WB (16)
ELISA (1)
ICC (1)
IF (2)
Peptide-ELISA (1)
rabbit (11)
mouse (6)
IgG (3)
IgG1 (5)
IgG3,k (1)
monoclonal mc (6)
polyclonal pc (11)
3G2 (1)
MANNES1A(7A12) (1)
OTI1E10 (2)
OTI9A11 (2)
96-Well Strip Plate (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (1)
Carrier-free (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (10)
aa30-283 (8)
aa1-285 (4)
aa4200-4250 (1)
No (20)
Tissue Homogenates (1)
GST, N-terminus (1)
His-T7 (1)
Human (2)
E. coli (1)
Wheat Germ Extract (1)
Select
SYNE1 / Nesprin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SYNE1 / Nesprin 1 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-SYNE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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SYNE1 / Nesprin 1 Mouse anti-Human Monoclonal (aa1-285) (OTI1E10) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SYNE1 / Nesprin 1 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-SYNE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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SYNE1 / Nesprin 1 Mouse anti-Human Monoclonal (aa1-285) (Carrier-free) (OTI1E10) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SYNE1 / Nesprin 1 Antibody - Normal human fibroblast cells stained with MANNES1A(7A12) + DAPI
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SYNE1 / Nesprin 1 Mouse anti-Human Monoclonal (MANNES1A(7A12)) Antibody
Rabbit, Mouse, Rat, Human
ICC, IF, WB
Unconjugated
0.1 mg/$482
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SYNE1 / Nesprin 1 Mouse anti-Human Monoclonal (3G2) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
SYNE1 / Nesprin 1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SYNE1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SYNE1. (1:2000)
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SYNE1 / Nesprin 1 Mouse anti-Human Monoclonal (aa1-285) (OTI9A11) Antibody
Human
WB
Unconjugated
100 µl/$434
SYNE1 / Nesprin 1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SYNE1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SYNE1. (1:2000)
Select
SYNE1 / Nesprin 1 Mouse anti-Human Monoclonal (aa1-285) (Carrier-free) (OTI9A11) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
SYNE1 / Nesprin 1 Antibody - Western blot of SYNE1 / Nesprin 1 antibody.
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SYNE1 / Nesprin 1 Rabbit anti-Human Polyclonal (aa30-283) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
SYNE1 / Nesprin 1 Antibody - Western blot of SYNE1 / Nesprin 1 antibody.
Select
SYNE1 / Nesprin 1 Rabbit anti-Human Polyclonal (aa30-283) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
SYNE1 / Nesprin 1 Antibody - Western blot of SYNE1 / Nesprin 1 antibody.
Select
SYNE1 / Nesprin 1 Rabbit anti-Human Polyclonal (aa30-283) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
SYNE1 / Nesprin 1 Antibody - Western blot of SYNE1 / Nesprin 1 antibody.
Select
SYNE1 / Nesprin 1 Rabbit anti-Human Polyclonal (aa30-283) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
SYNE1 / Nesprin 1 Antibody - Western blot of SYNE1 / Nesprin 1 antibody.
Select
SYNE1 / Nesprin 1 Rabbit anti-Human Polyclonal (aa30-283) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
SYNE1 / Nesprin 1 Antibody - Western blot of SYNE1 / Nesprin 1 antibody.
Select
SYNE1 / Nesprin 1 Rabbit anti-Human Polyclonal (aa30-283) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
SYNE1 / Nesprin 1 Antibody - Western blot of SYNE1 / Nesprin 1 antibody.
Select
SYNE1 / Nesprin 1 Rabbit anti-Human Polyclonal (aa30-283) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
SYNE1 / Nesprin 1 Antibody - Western blot of SYNE1 / Nesprin 1 antibody.
Select
SYNE1 / Nesprin 1 Rabbit anti-Human Polyclonal (aa30-283) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
SYNE1 / Nesprin 1 Antibody - Detection of human SYNE1 by western blot. Samples: Whole cell lysate and Nuclear Extract (50 µg) from HeLa cells. Antibody: Affinity purified rabbit anti-SYNE1 antibody used for WB at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Select
SYNE1 / Nesprin 1 Rabbit anti-Human Polyclonal (aa4200-4250) Antibody
Human
WB
Unconjugated
10 µg/$295; 100 µl/$514
SYNE1 / Nesprin 1 Antibody - Immunochemical staining of human SYNE1 in human skeletal muscle with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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SYNE1 / Nesprin 1 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
SYNE1 / Nesprin 1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SYNE1 / Nesprin 1 Protein - Recombinant Nesprin 1 By SDS-PAGE
Select
E. coli
His-T7
32.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
SYNE1 / Nesprin 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$834
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).