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STAT6

signal transducer and activator of transcription 6, interleukin-4 induced

STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

Gene Name: signal transducer and activator of transcription 6, interleukin-4 induced
Synonyms: STAT6, D12S1644, IL-4-STAT, Stat-6, STAT6B, STAT6C, STAT, interleukin4-induced, IL-4 Stat, Transcription factor IL-4 STAT
Target Sequences: NM_003153 NP_003144.3 P42226

Publications (2)

1
CT and Functional MRI to Evaluate Airway Mucus in Severe Asthma. Sarah Svenningsen, Ehsan Haider, Colm Boylan, Manali Mukherjee, Rachel L Eddy, Dante P I Capaldi, Grace Parraga, Parameswaran Nair. Chest. 2019 Jun;155:1178-1189. [Full Text Article] [PubMed:30910637]
2
PARP14 is a novel target in STAT6 mutant follicular lymphoma. Michael Mentz, William Keay, Carolin Dorothea Strobl, Martina Antoniolli, Louisa Adolph, Michael Heide, Axel Lechner, Sarah Haebe, Elisa Osterode, Robert Kridel, Christoph Ziegenhain, Lucas Esteban Wange, Johannes Adrian Hildebrand, Tanaya Shree, Elisabeth Silkenstedt, Annette M Staiger, German Ott, Heike Horn, Monika Szczepanowski, Julia Richter, Ronald Levy, Andreas Rosenwald, Wolfgang Enard, Ursula Zimber-Strobl, Michael von Bergwelt-Baildon, Wolfgang Hiddemann, Wolfram Klapper, Marc Schmidt-. Leukemia. 2022 September;36:2281-2292. [Full Text Article] [PubMed:35851155] [PMC:PMC9417990] Related Antibodies: LS-B6154.

☰ Filters
Antibodies (112)
ELISA Kits (16)
Proteins (11)
Cell-Based Phosphorylation (3)
Competitive EIA (1)
Custom (1)
Over-Expression Lysate (2)
Primary (112)
Recombinant (9)
Sandwich (11)
STAT6 (139)
Human (100)
Mouse (57)
Rat (42)
Bat (4)
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Chicken (1)
Chimpanzee (1)
Dog (13)
Gibbon (6)
Guinea pig (6)
Hamster (3)
Horse (6)
Monkey (11)
Non-Human Primate (1)
Orangutan (6)
Pig (8)
Porcine (1)
Rabbit (9)
Sheep (2)
IHC (47)
IHC-Fr (2)
IHC-P (18)
WB (92)
Flo (5)
ChIP-Seq (1)
ELISA (32)
ICC (5)
IF (12)
IP (11)
Peptide-ELISA (7)
rabbit (96)
mouse (16)
Product Group
IHCPlus (2)
IgG (61)
IgG1 (10)
IgG2a (1)
IgG2b,k (1)
monoclonal mc (18)
polyclonal pc (93)
recombinant monoclonal rmc (1)
177C322.1 (1)
6C10 (1)
7D3 (2)
EP325 (2)
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pTyr641 (17)
aa262-520 (8)
aa410-623 (8)
aa557-841 (8)
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C-Terminus (4)
aa614-663 (4)
580-660 aa (3)
aa600-650 (3)
Arg639 (1)
Internal (1)
Tyr641 (1)
aa342-640 (1)
aa608-657 (1)
aa612-661 (1)
aa620 (1)
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aa85-115 (1)
p641 (1)
p645 (1)
No (137)
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Low endotoxin level (3)
STAT6 Antibody - Anti-STAT6 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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STAT6 Mouse anti-Human Monoclonal (6C10) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
STAT6 Antibody - Anti-STAT6 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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STAT6 Rabbit anti-Human Polyclonal (aa614-663) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
STAT6 Antibody - Anti-STAT6 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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STAT6 Rabbit anti-Human Polyclonal (aa614-663) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
STAT6 Antibody - Anti-STAT6 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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STAT6 Rabbit anti-Human Polyclonal (aa614-663) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
STAT6 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using STAT6 (Phospho-Tyr641) Antibody. The picture on the right is blocked with the phospho peptide.
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STAT6 Rabbit anti-Human Polyclonal (pTyr641) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
STAT6 ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$641
STAT6 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
STAT6 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$798
STAT6 ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
STAT6 Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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STAT6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
STAT6 ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$556
STAT6 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using STAT6 (Phospho-Thr645) Antibody. The picture on the right is blocked with the phospho peptide.
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STAT6 Rabbit anti-Human Polyclonal (pThr645) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
STAT6 Antibody - Immunohistochemical analysis of STAT6 (pY641) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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STAT6 Rabbit anti-Human Polyclonal (pTyr641) Antibody
Rabbit, Mouse, Dog, Sheep, Bovine, Pig, Human, Monkey
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$315
STAT6 Antibody - Immunofluorescence of HeLa cells using STAT6 mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin
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STAT6 Mouse anti-Human Monoclonal (7D3) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µl/$435
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STAT6 Mouse anti-Human Monoclonal (aa630-650) Antibody
Mouse, Dog, Human
ELISA, WB
Unconjugated
100 µg/$845
STAT6 Antibody - STAT6 Antibody in Immunofluorescence (IF)
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STAT6 Mouse anti-Human Monoclonal (7D3) Antibody
Mouse, Rat, Non-Human Primate, Human
ChIP-Seq, ICC, IF, WB
Unconjugated
100 µl/$541
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STAT6 Rabbit anti-Human Monoclonal (EP325) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$438; 0.5 ml/$711; 1 ml/$1,029
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STAT6 Rabbit anti-Human Monoclonal (Ready-to-Use) (EP325) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$466; 7 ml/$620; 15 ml/$1,075
STAT6 Antibody - 1:200 staining mouse brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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STAT6 Rabbit anti-Human Polyclonal (pThr645) Antibody
Mouse, Rat, Human
IF, IHC, IP, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
STAT6 Antibody - 1:200 staining mouse ganstric tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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STAT6 Rabbit anti-Human Polyclonal (pTyr641) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
STAT6 Rabbit anti-Human Polyclonal (pTyr641) Antibody
Human
ELISA, Flo, ICC, IF, IP, WB
Unconjugated
100 µl/$717
Select
STAT6 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo
FITC Conjugated
25 Tests/$263; 100 Tests/$323
STAT6 Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT6 (Ab-645) antibody.
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STAT6 Rabbit anti-Human Polyclonal (p645) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
STAT6 Antibody - Immunohistochemistry image of paraffin-embedded human pancreatic cancer at a dilution of 1:100
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STAT6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
STAT6 Mouse anti-Human Monoclonal Antibody
Human
Flo, ICC, IF
Unconjugated
100 µl/$412
Viewing 1-25 of 139 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).