SRSF2 / SC35

serine/arginine-rich splicing factor 2

Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. Can bind to beta-globin mRNA and commit it to the splicing pathway. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment.

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Products

Antibodies (19)

ELISA Kits (8)

Proteins (4)

Type

Custom (5)

Over-Expression Lysate (2)

Primary (19)

Recombinant (2)

Sandwich (3)

Target

SRSF2 / SC35 (31)

Reactivity

Human (22)

Mouse (8)

Rat (8)

Bovine (3)

Chicken (4)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Monkey (3)

Pig (4)

Xenopus (3)

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Application

IHC (5)

IHC-P (5)

WB (19)

ELISA (2)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (19)

Product Group

IHCPlus (1)

Isotype

IgG (4)

Clonality

polyclonal pc (19)

Format

96-Well Strip Plate (8)

APC (1)

APC Conjugated (1)

Biotin Conjugated (2)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (9)

Epitope

aa14-221 (8)

C-Terminus (4)

aa76-105 (1)

aa9-39 (1)

Publications

No (30)

Yes (1)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (2)

Tag

GST (1)

His-GST (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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SRSF2 / SC35 Antibody (aa9-39) LS-C97287

(4.0) Rating

(1) Publication(s)

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (aa9-39) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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SRSF2 / SC35 Antibody (C-Terminus) LS-B9760

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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SRSF2 / SC35 Antibody (C-Terminus, HRP) LS-C468542

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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SRSF2 / SC35 Antibody (C-Terminus, Biotin) LS-C468540

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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SRSF2 / SC35 Antibody (C-Terminus, FITC) LS-C468541

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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Human SRSF2 / SC35 Protein (Recombinant His-GST) (aa14-221) - LS-G25555

Source:

E. coli

Tag:

His-GST

Molecular Weight:

54.1 kDa

Price:

10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142

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Human SRSF2 / SC35 Protein (Recombinant GST) (Full Length) - LS-G30380

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

45.43 kDa

Price:

10 µg/$479; 25 µg/$670

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SRSF2 / SC35 Antibody LS-C809031

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SRSF2 / SC35 Antibody (aa14-221) LS-C373319

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (aa14-221) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561

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SRSF2 / SC35 Antibody (aa14-221, HRP) LS-C713272

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (aa14-221) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702

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SRSF2 / SC35 Antibody (aa14-221, Biotin) LS-C688473

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (aa14-221) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596

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SRSF2 / SC35 Antibody (aa14-221, FITC) LS-C695451

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (aa14-221) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755

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SRSF2 / SC35 Antibody (aa14-221, Cy3) LS-C704253

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (aa14-221) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008

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SRSF2 / SC35 Antibody (aa14-221, APC) LS-C741448

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (aa14-221) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008

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SRSF2 / SC35 Antibody (aa14-221, PE) LS-C727338

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (aa14-221) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008

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SRSF2 / SC35 Antibody (aa14-221, APC, Cy7) LS-C736250

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (aa14-221) (APC, Cy7) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401

• Unconjugated
• HRP
• Biotin
• FITC
• Cy3
• APC
• PE
• More...
  • APC, Cy7

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • Cy3
  • APC
  • PE
  • APC, Cy7

Select

SRSF2 / SC35 Antibody LS-C752885

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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SRSF2 / SC35 Antibody LS-C413760

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$394

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SRSF2 / SC35 Antibody (aa76-105) LS-C169026

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal (aa76-105) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

SRSF2 / SC35 Antibody LS-C408726

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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SRSF2 / SC35 Antibody LS-C834209

Antibody:

SRSF2 / SC35 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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Mouse SRSF2 / SC35 (Custom ELISA) ELISA Kit - LS-F16228

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Rat SRSF2 / SC35 (Custom ELISA) ELISA Kit - LS-F16224

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Chicken SRSF2 / SC35 (Custom ELISA) ELISA Kit - LS-F16225

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

Select

Bovine SRSF2 / SC35 (Custom ELISA) ELISA Kit - LS-F16226

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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