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SPTA1 / Alpha Spectrin

spectrin, alpha, erythrocytic 1 (elliptocytosis 2)

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.

Gene Name: spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
Synonyms: SPTA1, EL2, Erythroid alpha-spectrin, HS3, Alpha-I spectrin, HPP, SPH3, SPTA
Target Sequences: NM_003126 NP_003117.2 P02549

☰ Filters
Antibodies (19)
ELISA Kits (2)
Proteins (2)
Over-Expression Lysate (2)
Primary (19)
Sandwich (2)
SPTA1 / Alpha Spectrin (23)
Human (20)
Mouse (5)
Rat (2)
IHC (3)
IHC-Fr (2)
IHC-P (8)
WB (15)
ELISA (7)
ICC (1)
IP (2)
Peptide-ELISA (1)
rabbit (11)
mouse (8)
IgG (6)
IgG1 (4)
IgG2b,k (4)
monoclonal mc (6)
polyclonal pc (9)
recombinant monoclonal rmc (4)
AF10 (2)
rSPTA1/1833 (2)
SPTA1/1810 (2)
SPTA1/1832 (2)
SPTA1/2939R (2)
96-Well Strip Plate (2)
Azide-free (4)
Biotin Conjugated (1)
BSA-free (2)
Carrier-free (2)
Concentrated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (16)
aa356-475 (4)
aa380-429 (4)
No (23)
Plasma (2)
Serum (2)
Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
SPTA1 / Alpha Spectrin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SPTA1 / Alpha Spectrin Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer tissue  using SPTA1 Polyclonal Antibody at dilution of 1:80(×200)
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SPTA1 / Alpha Spectrin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
SPTA1 / Alpha Spectrin Mouse anti-Human Monoclonal (Concentrated) (AF10) Antibody
Human
ICC, IHC, IHC-Fr, IP, WB
Unconjugated, Concentrated
1 ml/$589
Select
SPTA1 / Alpha Spectrin Mouse anti-Human Monoclonal (AF10) Antibody
Human
IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$924
SPTA1 / Alpha Spectrin Antibody - IHC staining of FFPE human placenta with SPTA1 antibody (clone SPTA1/1810). Required HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
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SPTA1 / Alpha Spectrin Mouse anti-Human Monoclonal (SPTA1/1810) Antibody
Human
ELISA, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
SPTA1 / Alpha Spectrin Antibody - IHC staining of FFPE human tonsil with Spectrin alpha 1 antibody (clone SPTA1/1832). Required HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
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SPTA1 / Alpha Spectrin Mouse anti-Human Monoclonal (SPTA1/1832) Antibody
Human
ELISA, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
SPTA1 / Alpha Spectrin Antibody - IHC staining of FFPE human placenta with SPTA1 antibody (clone SPTA1/1810). Required HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
Select
SPTA1 / Alpha Spectrin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPTA1/1810) Antibody
Human
ELISA, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
SPTA1 / Alpha Spectrin Antibody - IHC staining of FFPE human tonsil with Spectrin alpha 1 antibody (clone SPTA1/1832). Required HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
Select
SPTA1 / Alpha Spectrin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPTA1/1832) Antibody
Human
ELISA, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
SPTA1 / Alpha Spectrin Antibody - Formalin-fixed, paraffin-embedded human Pancreas stained with Spectrin alpha 1 Rabbit Recombinant Monoclonal Antibody (SPTA1/2939R).
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SPTA1 / Alpha Spectrin Rabbit anti-Human Recombinant Monoclonal (aa356-475) (SPTA1/2939R) Antibody
Human
ELISA, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
SPTA1 / Alpha Spectrin Antibody - Formalin-fixed, paraffin-embedded human Pancreas stained with Spectrin alpha 1 Rabbit Recombinant Monoclonal Antibody (SPTA1/2939R).
Select
SPTA1 / Alpha Spectrin Rabbit anti-Human Recombinant Monoclonal (aa356-475) (Azide-free, Carrier-free) (SPTA1/2939R) Antibody
Human
ELISA, IHC-P, WB
Unconjugated, Azide-free, Carrier-free
100 µg/$574
Select
SPTA1 / Alpha Spectrin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SPTA1 / Alpha Spectrin Antibody - Formalin-fixed, paraffin-embedded Human Placenta stained with Spectrin alpha 1 Mouse Recombinant Monoclonal Antibody (rSPTA1/1833).
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SPTA1 / Alpha Spectrin Mouse anti-Human Recombinant Monoclonal (aa356-475) (rSPTA1/1833) Antibody
Human
IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
SPTA1 / Alpha Spectrin Antibody - Formalin-fixed, paraffin-embedded Human Placenta stained with Spectrin alpha 1 Mouse Recombinant Monoclonal Antibody (rSPTA1/1833).
Select
SPTA1 / Alpha Spectrin Mouse anti-Human Recombinant Monoclonal (aa356-475) (Azide-free, Carrier-free) (rSPTA1/1833) Antibody
Human
IHC-P, WB
Unconjugated, Azide-free, Carrier-free
100 µg/$574
Select
SPTA1 / Alpha Spectrin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SPTA1 / Alpha Spectrin Antibody - SPTA1 / Alpha Spectrin antibody Western Blot of Fetal Liver. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SPTA1 / Alpha Spectrin Rabbit anti-Human Polyclonal (aa380-429) Antibody
Human
WB
Unconjugated
100 µl/$424
SPTA1 / Alpha Spectrin Antibody - SPTA1 / Alpha Spectrin antibody Western Blot of Fetal Liver. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SPTA1 / Alpha Spectrin Rabbit anti-Human Polyclonal (aa380-429) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
SPTA1 / Alpha Spectrin Antibody - SPTA1 / Alpha Spectrin antibody Western Blot of Fetal Liver. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SPTA1 / Alpha Spectrin Rabbit anti-Human Polyclonal (aa380-429) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
SPTA1 / Alpha Spectrin Antibody - SPTA1 / Alpha Spectrin antibody Western Blot of Fetal Liver. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SPTA1 / Alpha Spectrin Rabbit anti-Human Polyclonal (aa380-429) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
SPTA1 / Alpha Spectrin Antibody
Select
SPTA1 / Alpha Spectrin Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
SPTA1 / Alpha Spectrin Antibody - Western blot analysis of extracts of various cell lines, using SPTA1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Select
SPTA1 / Alpha Spectrin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SPTA1 / Alpha Spectrin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SPTA1 / Alpha Spectrin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
281.06 kDa
20 µg/$215
SPTA1 / Alpha Spectrin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
281.06 kDa
100 µg/$710
Viewing 1-23 of 23 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).