Pre-treatment with antigen retrieval. With the help of some antibodies CD43 has also been localized on non-haematopoietic tumours (melanoma, mamma carcinoma, and ovarian carcinoma), but the main purpose of MT1 antibody is the typing of T-cell lymphoma in tissue sections and bone marrow cell smears. CD43 (or Leukosialin) is a membrane sialoglycoprotein, which is expressed by all thymocytes and T-cells. It is also found on granulocytes, monocytes, macrophages, NK-cells, platelets, activated B-cells, plasma cells and haematopoietic stem cells. Normal B-cells don't express CD43. CD43 possibly interacts with CD54 (ICAM-1) and causes antigen specific T-cell activation. Human CD43 (95-160 kDa sialoglycoprotein) MW depending of cell type.
PBS, pH 7.3, 0.09% Sodium Azide
For research use only. Intended for use by laboratory professionals.
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