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Catalog Number Size Price
LS-C39294-200 200 µg $674 
Antibody

Monoclonal Mouse anti‑Human SMC1A / SMC1 Antibody (phospho‑Ser957, WB) LS‑C39294

Monoclonal Mouse anti‑Human SMC1A / SMC1 Antibody (phospho‑Ser957, WB) LS‑C39294

Antibody:
SMC1A / SMC1 Mouse anti-Human Monoclonal (pSer957) Antibody
Application:
WB
Reactivity:
Human, Monkey, Bovine, Dog, Rabbit
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$674
LS-C39294-200
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
SMC1A / SMC1 Mouse anti-Human Monoclonal (pSer957) Antibody
Application:
WB
Reactivity:
Human, Monkey, Bovine, Dog, Rabbit
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
SMC1 antibody LS-C39294 is an unconjugated mouse monoclonal antibody to SMC1 (SMC1A) (pSer957) from human. It is reactive with human, bovine, dog and other species. Validated for WB.
Target
Human SMC1A / SMC1
Synonyms
SMC1A | CDLS2 | DXS423E | KIAA0178 | SB1.8 | SMC protein 1A | SMC1 | SMC1L1 | SMC-1-alpha | SMC-1A | SMCB
Host
Mouse
Reactivity
Human, Monkey, Bovine, Dog, Rabbit (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
KLH-conjugated, synthetic peptide corresponding to aa 951-962, (SQEEGS[pS]QGEDS) of human SMC1 (Structural Maintenance of Chromosome 1). The immunizing sequence is identical in bovine and has 11/12 identical amino acids in mouse and xenopus.
Epitope
pSer957
Specificity
Recognizes phospho-SMC1 (Ser957), Mr 150kD. Species cross-reactivity: Human and mouse. Predicted to cross-react with Xenopus and bovine based on sequence homology.
Applications
  • Western blot (1 - 2 µg/ml)
Usage
Suitable for use in Western Blot. Western Blot: 1-2 ug/ml detects phospho-SMC1 in RIPA lysates from irradiated GMO536 cells and hydroxyurea treated HEK293 cells. Cell lysates from untreated and irradiated GMO536 cells were resolved by electrophoresis, transferred to nitrocellulose and probed with anti-phospho-SMC1 (Ser957) (2 ug/ml). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system.
Presentation
0.1 M Tris-Glycine, pH 7.4, 0.15 M NaCl, 0.05% Sodium Azide, 30% Glycerol
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About SMC1A / SMC1
Q14683 NM_006306 NP_006297.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 8/15/2022