Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
Western blot (1 - 10 µg/ml)
ELISA (0.5 - 1 µg/ml)
SLC20A1 antibody was raised against a 17aa synthetic peptide within the 4th putative cytoplasmic domain of mouse PiT-1/GLVR-1 (KLH).
Recognizes mouse PiT 1. Species sequence Homology: Rat - 100%; Human - 82%. No significant sequence homology is observed with PiT-2 or NaPi-Type I, -2, or IV transporters.
Suitable for use in Western Blot and ELISA. Western Blot: 1-10 ug/ml (ECL). A band of 85-90kD has been detected in brush border membrane. Additional bands of 70-72kD may represent proteolytic fragments of PiT-1. ELISA: 0.5-1 ug/ml; Control peptide can be used to coat ELISA plates at 1 ug/ml.
PBS, pH 7.4, 0.1% BSA
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification.