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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SLC1A2 / EAAT2 / GLT‑1 Antibody (aa546‑565) LS‑C15448

Antibody

SLC1A2 / EAAT2 / GLT‑1 Antibody (aa546‑565) LS‑C15448

Antibody:
Guinea pig Polyclonal to Rat SLC1A2 / EAAT2 / GLT-1
Application:
IHC
Reactivity:
Rat, Human, Monkey, Mouse, Rabbit
Format:
Unconjugated, Unmodified
Price
Catalog Number
$740 
LS-C15448-50
Toll Free North America
866-819-4732

Overview

Antibody:
Guinea pig Polyclonal to Rat SLC1A2 / EAAT2 / GLT-1
Application:
IHC
Reactivity:
Rat, Human, Monkey, Mouse, Rabbit
Format:
Unconjugated, Unmodified

Specifications

Description
GLT-1 antibody LS-C15448 is an unconjugated guinea pig polyclonal antibody to GLT-1 (SLC1A2 / EAAT2) from human, mouse, rat and other species. Validated for IHC. Cited in 1 publication.
Target
Rat SLC1A2 / EAAT2 / GLT-1
Host
Guinea pig
Reactivity
Rat, Human, Monkey, Mouse, Rabbit (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • IHC (1:1000 - 1:4000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide (AANGKSADCSVEEEPWKREK) from the carboxy-terminus of rat GLT-1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Rabbit (100%); Bat, Bovine, Dog, Pig (95%); Horse (90%); Turkey, Chicken, Platypus (80%).
Epitope
aa546-565
Specificity
Recognizes rat Glial Glutamate Transporter GLT-1 (EAAT2). Species Reactivity: Rat. Species sequence homology: human.
Usage
Suitable for use in Immunohistochemistry. Immunohistochemistry: 1:1000-1:4000, using a DAB detection system on adult rat forebrain fixed with 4% paraformaldehyde. IHC-P, 1:1000 optical staining with with EDTA pH 8.0 antigen retrieval.
Presentation
Whole antiserum with 0.05% Sodium Azide
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About SLC1A2 / EAAT2 / GLT-1
P43004 NM_004171 NP_004162.2

Publications (1)

Pharmacological inhibitions of glutamate transporters EAAT1 and EAAT2 compromise glutamate transport in photoreceptor to ON-bipolar cell synapses. Tse DY, Chung I, Wu SM. Vision research. 2014 103:49-62. (IHC; Rat)

Reviews (0)

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Requested From: United States
Date Requested: 7/22/2019
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