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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SLC18A2 / VMAT2 Antibody (aa502-515) LS-C18507

Note: This antibody replaces LS-C18506
VMAT2 antibody LS-C18507 is an unconjugated rabbit polyclonal antibody to VMAT2 (SLC18A2) from rat, dog and horse. Validated for IHC.
Catalog
Size
Price
LS-C18507-50
50 µl
$995
Description
VMAT2 antibody LS-C18507 is an unconjugated rabbit polyclonal antibody to VMAT2 (SLC18A2) from rat, dog and horse. Validated for IHC.
Target
Rat SLC18A2 / VMAT2
Host
Rabbit
Reactivity
Rat, Dog, Horse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen (1:800 - 1:1200)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
SLC18A2 / VMAT2 antibody was raised against synthetic peptide [C-QSYPIGDDEESESD-OH] from the C-terminus of rat VMAT2 conjugated to BSA. Percent identity by BLAST analysis: Gorilla, Gibbon, Monkey, Rat, Elephant, Dog, Horse (100%); Human, Marmoset, Panda (93%); Mouse, Bat, Bovine, Turkey, Chicken (86%).
Epitope
aa502-515
Specificity
Recognizes rat VMAT2. Recognizes monoaminergic neurons of the CNS, the ECL-cells of the stomach, as well as enteric nerve fibers. Absorption with 10-100 ug immunogen per ml diluted antiserum abolishes staining. Species cross-reactivity: Guinea pig (in fundus tissue, only positive on nerve fibers; endocrine cells are negative); most mammals including human, canine, mouse, hamster, as well as chicken and frog. Negative with porcine intestinal tissue.
Usage
Suitable for use in Immunohistochemistry. Immunohistochemistry (Frozen sections): 1:800-1:1200 using FITC. Incubation time overnight at 4?C. Absorption with 10-100 ug immunogen per ml diluted antiserum abolishes staining. Dilute after reconstitution with 0.15 M PBS, 1% BSA and 0.1% sodium azide. Positive control: Frozen sections of rat small intestine.
Presentation
Lyophilized
Reconstitution
50 µl deionized water
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
About SLC18A2 / VMAT2
Q05940 NM_003054 NP_003045.2

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Requested From: United States
Date Requested: 4/21/2019
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