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SIPR3 / EDG3 / S1P3
sphingosine-1-phosphate receptor 3
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
| Gene Name: | sphingosine-1-phosphate receptor 3 |
| Family/Subfamily: | GPCR , Lysophospholipid/Lysosphingolipid |
| Synonyms: | S1PR3, EDG-3, EDG3, LPB3, S1P receptor EDG3, S1P3, S1P receptor Edg-3, S1P receptor 3 |
| Target Sequences: | NM_005226 NP_005217.2 Q99500 |
Publications (3)
1
Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions. Ruben Van Doorn, Jack Van Horssen, Dennis Verzijl, Maarten Witte, Eric Ronken, Bert Van Het Hof, Kim Lakeman, Christine D. Dijkstra, Paul Van Der Valk, Arie Reijerkerk, Astrid E. Alewijnse, Stephan L. M. Peters, Helga E. De Vries. Glia. 2010 58:1465-76. (ICC, IHC-Fr; Human, Hamster)
[Full Text Article]
[PubMed:20648639]
Related Antibodies: LS-B2155.
2
Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases. Gril B, Paranjape AN, Woditschka S, Hua E, Dolan EL, Hanson J, Wu X, Kloc W, Izycka-Swieszewska E, Duchnowska R, Peksa R, Biernat W, Jassem J, Nayyar N, Brastianos PK, Hall OM, Peer CJ, Figg WD, Pauly GT, Robinson C, Difilippantonio S, Bialecki E, Metellus P, Schneider JP, Steeg PS. Nature communications. 2018 July;9:2705. (Human)
[Full Text Article]
[PubMed:30006619]
[PMC:PMC6045677]
Related Antibodies: LS-B2155.
3
Sphingosine-1-phosphate receptor 3 mediates sphingosine-1-phosphate induced release of weibel-palade bodies from endothelial cells. van Hooren KW, Spijkers LJ, van Breevoort D, Fernandez-Borja M, Bierings R, van Buul JD, Alewijnse AE, Peters SL, Voorberg J. PloS one. 2014 9:e91346. [Full Text Article]
[PubMed:24632890]
[PMC:PMC3954688]
Related Antibodies: LS-B2155.
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SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa12-25) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$485
Cancer
Fast Shipping
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
SIPR3 / EDG3 / S1P3 Mouse anti-Human Monoclonal (2G11) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa300-350) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$386
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa201-250) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa201-250) (HRP) Antibody
Human, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa201-250) (Biotin) Antibody
Human, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (90-170 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa1-30) Antibody
WB
Unconjugated
200 µl/$734
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Mouse, Human
ELISA, ICC, IHC, IHC-P, WB
Biotin Conjugated
200 µl/$952
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Mouse, Human
ELISA, ICC, IHC, IHC-P, WB
FITC Conjugated
200 µl/$952
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Mouse, Human
ELISA, ICC, IHC, IHC-P, WB
PE Conjugated
200 µl/$952
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Mouse, Human
ELISA, ICC, IHC, IHC-P, WB
APC Conjugated
200 µl/$952
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, ICC, IHC, IHC-P, WB
HRP Conjugated, Azide-free
200 µl/$952
Cancer
Fast Shipping
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$357
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal (Phe155) Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
SIPR3 / EDG3 / S1P3 Rabbit anti-Human Polyclonal Antibody
Human
ICC, WB
Unconjugated
1 Each/$431
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