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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SIGIRR Antibody (aa334‑358) LS‑C816
Note: This antibody replaces LS-C91387
SIGIRR antibody LS-C816 is an unconjugated rabbit polyclonal antibody to SIGIRR from human and mouse. Validated for WB.
Catalog
Size
Price
LS-C816-100
100 µg (0.5 mg/ml)
$335

Popular SIGIRR Products

Antibody
Species: Human
Applications: Flow Cytometry
Western blot of recombinant SIGIRR.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse
Applications: IHC, Western blot
Anti-SIGIRR antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5817 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Immunohistochemistry of A549 cells with Rabbit anti-Mouse SIGIRR
Species: Mouse, Human
Applications: IHC, IHC - Frozen, ICC, Western blot
Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

SIGIRR antibody LS-C816 is an unconjugated rabbit polyclonal antibody to SIGIRR from human and mouse. Validated for WB.

Specifications

Target
Human SIGIRR
Synonyms
SIGIRR, TIR8, Toll/interleukin-1 receptor 8
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (5 µg/ml)
Immunogen
SIGIRR antibody was raised against synthetic peptide from human SIGIRR.
Epitope
aa334-358
Specificity
A synthetic peptide corresponding to amino acids334-358 of human Tir8.
Presentation
PBS, 0.2% Gelatin
Storage
Short term: 4°C; Long term: -70°C.
Restrictions
For research use only.
About SIGIRR
SIGIRR is a member of the Toll-like receptor-interleukin 1 receptor superfamily. Members of this family are defined by the presence of an intracellular Toll-IL-1R (TIR) domain. The Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. Q6IA17 NM_021805 NP_068577.2


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Images

Western blot

Western blot of human TIR8 in 15 ugs of (A) human kidney and (B) mouse kidney cell lysate using antibody at 0.5 ug/ml.
Western blot of human TIR8 in 15 ugs of (A) human kidney and (B) mouse kidney cell lysate using antibody at 0.5 ug/ml.

Western blot

Western blot of human TIR8 in 15 ugs of (A) human kidney and (B) mouse kidney cell lysate using antibody at 0.5 ug/ml.
Western blot of human TIR8 in 15 ugs of (A) human kidney and (B) mouse kidney cell lysate using antibody at 0.5 ug/ml.

Western blot

Western blot of human TIR8 in 15 ugs of (A) human kidney and (B) mouse kidney cell lysate using antibody at 0.5 ug/ml.
Western blot of human TIR8 in 15 ugs of (A) human kidney and (B) mouse kidney cell lysate using antibody at 0.5 ug/ml.

Western blot

Western blot of human TIR8 in 15 ugs of (A) human kidney and (B) mouse kidney cell lysate using antibody at 0.5 ug/ml.
Western blot of human TIR8 in 15 ugs of (A) human kidney and (B) mouse kidney cell lysate using antibody at 0.5 ug/ml.

Requested From: United States
Date Requested: 10/17/2018

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