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SERPINE1 / PAI-1

Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

SERPINE1 / PAI-1 is a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Family/Subfamily: Serine Protease Inhibitor
Synonyms: SERPINE1, PAI1, PLANH1, PAI-1, Serpin E1
Target Sequences: NM_000602 NP_000593.1 P05121

Publications (1)

1
BDNF-TrkB signaling through Erk1/2 MAPK phosphorylation mediates the enhancement of fear memory induced by glucocorticoids. Revest JM, Le Roux A, Roullot-Lacarrière V, Kaouane N, Vallée M, Kasanetz F, Rougé-Pont F, Tronche F, Desmedt A, Piazza PV. Molecular psychiatry. 2014 19:1001-9. (WB; Rat) [Full Text Article] [PubMed:24126929] [PMC:PMC4195976] Related Antibodies: LS-C81062.

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Antibodies (191)
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SERPINE1 / PAI-1 Antibody - Anti-SERPINE1 / PAI-1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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SERPINE1 / PAI-1 Goat anti-Human Polyclonal (aa71-85) Antibody
Human
ELISA, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
SERPINE1 / PAI-1 Antibody - Anti-SERPINE1 / PAI-1 antibody IHC of human placenta, decidual cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
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SERPINE1 / PAI-1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
SERPINE1 / PAI-1 Antibody - Anti-SERPINE1 / PAI-1 antibody IHC of human vascular endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
SERPINE1 / PAI-1 Antibody - Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal (aa31-80) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
SERPINE1 / PAI-1 Antibody - Immunohistochemistry-Paraffin: PAI1/Serpine1 Antibody - Staining of PAI1/Serpine 1 in mouse pancreas.
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SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal (aa300-400) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$386
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SERPINE1 / PAI-1 Mouse anti-Human Monoclonal (3 PAI) Antibody
Human
ELISA
Unconjugated
500 µg/$768
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SERPINE1 / PAI-1 Mouse anti-Human Monoclonal (MA-55F4C12) Antibody
Mouse, Rat, Human
Func
Unconjugated
100 µg/$516
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SERPINE1 / PAI-1 Sheep anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
200 µg/$702
SERPINE1 / PAI-1 Antibody - ICC/IF analysis of PAI1 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human PAI1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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SERPINE1 / PAI-1 Mouse anti-Human Monoclonal (AT1C5) Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
SERPINE1 / PAI-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.2 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Media, Plasma, Serum, Tissue Extracts
1 Plate/$896
SERPINE1 / PAI-1 ELISA Kit
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Functional
96-Well Strip Plate
Human
0.125 - 100 U/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$896
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rhesus monkey
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Tissue Homogenates
1 Plate/$940
SERPINE1 / PAI-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Tissue Homogenates
1 Plate/$610
SERPINE1 / PAI-1 Antibody - Western Blot analysis of SERPINE1 expression in transfected 293T cell line by SERPINE1 monoclonal antibody (M01), clone 3F2.Lane 1: SERPINE1 transfected lysate(45.1 KDa).Lane 2: Non-transfected lysate.
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SERPINE1 / PAI-1 Mouse anti-Human Monoclonal (3F2) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$423
SERPINE1 / PAI-1 Antibody - Western blot of PAI-1 antibody
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SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SERPINE1 / PAI-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
SERPINE1 / PAI-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Dog
0.2 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$896
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SERPINE1 / PAI-1 Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, IHC, WB
Unconjugated
1 mg/$1,119
SERPINE1 / PAI-1 Antibody - PAI1 Antibody in Immunohistochemistry (IHC)
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SERPINE1 / PAI-1 Mouse anti-Human Monoclonal (1D5) Antibody
Mouse, Human
Flo, IHC, WB
Unconjugated
100 µg/$503
SERPINE1 / PAI-1 ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rabbit
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$1,100
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SERPINE1 / PAI-1 ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
23 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$479
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SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
100 µg/$416; 1 mg/$554; 10 mg/$3,732
Viewing 1-25 of 274 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).